Nwoye Luke O, Al-Shehri Mohammed A
Department of Physiology, King Khalid University, College of Medicine and Medical Sciences, Abha, Kingdom of Saudi Arabia.
Saudi Med J. 2003 Dec;24(12):1341-6.
Human body surface area (BSA) is the preferred denominator for physiological indices of body metabolism and for drug dosages. The Du Bois and Du Bois height/weight nomogram, used for fast and convenient estimation of patients BSA, is not suitable for all populations due to ethnic differences in body shape and build. The purpose of this study was to obtain direct measurements of BSA and use the data to construct a prediction formula for Saudi male adults.
Body surface area was measured in 21 adult male Saudis at Assir Central Hospital in Abha, Kingdom of Saudi Arabia between 2000 and 2003, using a coating technique. Areas of the coating material were determined with a compensating planimeter. Other anthropometric indices were measured or calculated according to standard procedures. Measured values of BSA were subjected to linear regression analysis using the least squares method to obtain a formula for predicting BSA from heights and weights.
Mean body mass index (BMI) was 25.1 +/- 1.6 kg/m2; linearity, 2.46 +/- 0.13 cm/kg; surface to mass ratio, 0.025 +/- 0.0008 m2/kg; relative sitting height (RSH), 0.51 +/- 0.005. The closest fit to measured BSA values was given by the biexponential regression equation: BSA=0.02036 x H(0.516) x W(0.427) +/- 0.01283. This formula predicts BSA of Saudi male adults more accurately than all existing equations tested and yields a convenient BSA table for Saudis.
The use of our formula, with prediction accuracy superior to those of existing formulae, should facilitate the establishment of normal values of other physiological indices. It should also lead to more reliable and precise drug dosages and expedite rapid decision making in critical care situations.
人体表面积（BSA）是身体代谢生理指标和药物剂量的首选分母。用于快速便捷估算患者BSA的杜波依斯身高/体重列线图，由于体型和身材的种族差异，并不适用于所有人群。本研究的目的是获取BSA的直接测量值，并利用这些数据构建沙特成年男性的预测公式。
2000年至2003年期间，在沙特阿拉伯王国阿卜哈的阿西尔中央医院，对21名成年沙特男性使用涂层技术测量了人体表面积。用补偿式求积仪测定涂层材料的面积。其他人体测量指标按照标准程序进行测量或计算。对测量得到的BSA值采用最小二乘法进行线性回归分析，以获得根据身高和体重预测BSA的公式。
平均体重指数（BMI）为25.1±1.6kg/m²；线性度为2.46±0.13cm/kg；表面积与质量比为0.025±0.0008m²/kg；相对坐高（RSH）为0.51±0.005。双指数回归方程对测量得到的BSA值拟合度最佳：BSA=0.02036×H(0.516)×W(0.427)±0.01283。该公式比所有测试过的现有方程更准确地预测了沙特成年男性的BSA，并得出了一个方便的沙特人BSA表格。
使用我们的公式，其预测准确性优于现有公式，应有助于建立其他生理指标的正常值。它还应能实现更可靠、精确的药物剂量，并在重症监护情况下加快快速决策。
