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小儿实体器官移植中的感染并发症

Infectious complications in pediatric solid organ transplantation.

作者信息

Keough William L, Michaels Marian G

机构信息

Division of Allergy, Immunology and Infectious Diseases, Children's Hospital of Pittsburgh, 3705 Fifth Avenue, Pittsburgh, PA 15213, USA.

出版信息

Pediatr Clin North Am. 2003 Dec;50(6):1451-69, x. doi: 10.1016/s0031-3955(03)00126-3.

Abstract

Transplantation has emerged as one of the remarkable achievements of the latter half of the twentieth century for treatment of many end-stage organ disorders. Survival in pediatric solid organ transplantation continues to improve as strategies for immunosuppression, prevention and treatment of infectious complications progress. This article presents the summaries of the common and opportunistic pathogens that cause infectious complications for the pediatric transplant recipient. In addition, an approach to the pediatric transplant patient who presents with specific symptoms suggestive of infection is provided.

摘要

移植已成为20世纪后半叶治疗许多终末期器官疾病的显著成就之一。随着免疫抑制策略以及感染并发症预防和治疗方法的不断进步,小儿实体器官移植的存活率持续提高。本文总结了导致小儿移植受者感染并发症的常见病原体和机会性病原体。此外,还提供了针对出现提示感染的特定症状的小儿移植患者的处理方法。

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