Schnorrer Frank, Dickson Barry J
Institute of Molecular Biotechnology of the Austrian Academy of Sciences, Dr. Bohr-Gasse 7, A-1030, Vienna, Austria.
Curr Biol. 2004 Jan 6;14(1):R19-21. doi: 10.1016/j.cub.2003.12.016.
Hedgehog and Wnt family proteins can act as classic developmental morphogens to pattern a field of nai;ve cells. Surprising new studies show that members of these same protein families also act as guidance cues for growing axons in the developing nervous system.
刺猬蛋白和Wnt家族蛋白可作为经典的发育形态发生素,对一群未分化细胞进行模式化。令人惊讶的新研究表明,这些相同蛋白家族的成员在发育中的神经系统中也作为生长轴突的引导信号。