Fertil Steril. 2004 Jan;81(1):19-25. doi: 10.1016/j.fertnstert.2003.10.004.
Since the 1990 National Institutes of Health-sponsored conference on polycystic ovary syndrome (PCOS), it has become appreciated that the syndrome encompasses a broader spectrum of signs and symptoms of ovarian dysfunction than those defined by the original diagnostic criteria. The 2003 Rotterdam consensus workshop concluded that PCOS is a syndrome of ovarian dysfunction along with the cardinal features hyperandrogenism and polycystic ovary (PCO) morphology. PCOS remains a syndrome, and as such no single diagnostic criterion (such as hyperandrogenism or PCO) is sufficient for clinical diagnosis. Its clinical manifestations may include menstrual irregularities, signs of androgen excess, and obesity. Insulin resistance and elevated serum LH levels are also common features in PCOS. PCOS is associated with an increased risk of type 2 diabetes and cardiovascular events.
自1990年美国国立卫生研究院主办关于多囊卵巢综合征（PCOS）的会议以来，人们逐渐认识到，该综合征所涵盖的卵巢功能障碍体征和症状范围，比最初诊断标准所定义的更为广泛。2003年鹿特丹共识研讨会得出结论，PCOS是一种卵巢功能障碍综合征，其主要特征为高雄激素血症和多囊卵巢（PCO）形态。PCOS仍然是一种综合征，因此没有单一的诊断标准（如高雄激素血症或PCO）足以用于临床诊断。其临床表现可能包括月经不规律、雄激素过多的体征以及肥胖。胰岛素抵抗和血清LH水平升高也是PCOS的常见特征。PCOS与2型糖尿病和心血管事件的风险增加相关。
