Berry Daniel J, von Knoch Marius, Schleck Cathy D, Harmsen W Scott
Mayo Clinic, Rochester, MN 55905, USA.
J Bone Joint Surg Am. 2004 Jan;86(1):9-14. doi: 10.2106/00004623-200401000-00003.
A widely variable prevalence of dislocation after total hip arthroplasty has been reported, partly because of varying durations of follow-up for this specific end-point. The effect of demographic factors on the long-term risk of dislocation as a function of time after total hip arthroplasty is not well understood. The purpose of the present study was to determine the risk of dislocation as a function of time after Charnley total hip arthroplasty and to investigate the demographic factors that influence the cumulative risk of dislocation.
Six thousand six hundred and twenty-three consecutive primary Charnley total hip arthroplasties were performed in 5459 patients at one institution between 1969 and 1984. The patients included 2869 female patients and 2590 male patients with a mean age of sixty-three years. All procedures were performed with a 22-mm femoral head, and all femoral and acetabular components were fixed with cement. The patients were followed at routine intervals and were specifically queried about dislocation. The cumulative risk of dislocation was calculated with use of the Kaplan-Meier method.
Three hundred and twenty hips (4.8%) dislocated. The cumulative risk of a first-time dislocation was 1% at one month and 1.9% at one year and then rose at a constant rate of approximately 1% every five years to 7% at twenty-five years for patients who were alive and had not had a revision by that time. Multivariate analysis revealed that the relative risk of dislocation for female patients (as compared with male patients) was 2.1 and that the relative risk for patients who were seventy years old or more (as compared with those who were less than seventy years old) was 1.3. Three underlying diagnoses-osteonecrosis of the femoral head, acute fracture or nonunion of the proximal part of the femur, and inflammatory arthritis-were associated with a significantly greater risk of dislocation than osteoarthritis was.
The cumulative long-term risk of dislocation after total hip arthroplasty is considerably greater than has been reported in short-term studies. The incidence of dislocation is highest in the first year after arthroplasty and then continues at a relatively constant rate for the life of the arthroplasty. Patients at highest risk are female patients and those with a diagnosis of osteonecrosis of the femoral head or an acute fracture or nonunion of the proximal part of the femur.
Prognostic study, Level II-1 (retrospective study). See Instructions to Authors for a complete description of levels of evidence.
全髋关节置换术后脱位的发生率差异很大,部分原因是针对这一特定终点的随访时间各不相同。人口统计学因素对全髋关节置换术后脱位长期风险随时间变化的影响尚未得到充分了解。本研究的目的是确定Charnley全髋关节置换术后脱位风险随时间的变化情况,并调查影响脱位累积风险的人口统计学因素。
1969年至1984年间,在一家机构为5459例患者连续实施了6623例初次Charnley全髋关节置换术。患者包括2869例女性和2590例男性,平均年龄63岁。所有手术均使用22毫米股骨头,所有股骨和髋臼组件均用骨水泥固定。对患者进行定期随访,并专门询问脱位情况。使用Kaplan-Meier方法计算脱位的累积风险。
320髋(4.8%)发生脱位。初次脱位的累积风险在1个月时为1%,1年时为1.9%,然后以约每年1%的恒定速率上升,到25年时,对于仍存活且未进行翻修的患者,累积风险达到7%。多变量分析显示,女性患者(与男性患者相比)脱位的相对风险为2.1,70岁及以上患者(与70岁以下患者相比)脱位的相对风险为1.3。三种潜在诊断——股骨头坏死、股骨近端急性骨折或骨不连以及炎性关节炎——与脱位风险显著高于骨关节炎。
全髋关节置换术后脱位的累积长期风险远高于短期研究报告的结果。脱位发生率在置换术后第一年最高,然后在置换关节的使用寿命期间以相对恒定的速率持续存在。脱位风险最高的患者是女性以及诊断为股骨头坏死或股骨近端急性骨折或骨不连的患者。
预后研究,II-1级(回顾性研究)。有关证据水平的完整描述,请参阅作者须知。