Kobayashi Seneki, Sugano Nobuhiko, Ando Wataru, Fukushima Wakaba, Kondo Kyoko, Sakai Takashi
The Investigation Committee on Osteonecrosis of the Femoral Head under the Ministry of Health, Labour and Welfare, Tokyo; Department of Orthopaedic Surgery, Suwa Red Cross Hospital, Suwa, Japan.
The Investigation Committee on Osteonecrosis of the Femoral Head under the Ministry of Health, Labour and Welfare, Tokyo; epartment of Orthopaedic Medical Engineering, Osaka University Graduate School of Medicine, Suita, Japan.
Acta Orthop. 2025 Apr 17;96:348-355. doi: 10.2340/17453674.2025.43473.
Nontraumatic osteonecrosis of the femoral head (ONFH) patients are at a higher dislocation risk after primary total hip arthroplasties (THAs) than osteoarthrosis patients. It has not been clear how large prosthetic heads should be to reduce dislocation. A nationwide multicenter follow-up cohort study of THAs performed for ONFH aimed to evaluate risk factors associated with dislocation and whether larger head size could reduce the dislocation risk.
A multivariable logistic regression model analyzed factors associated with dislocation in 5,983 THAs performed for ONFH between 1996 and 2022 with a median of 7.1 (0.5-27)-year follow-up. Patient age at surgery was 52 years and BMI was 22.9, as medians. A posterior approach was employed in 59%. The head diameter was 22 mm in 4%, 26 mm in 15%, 28 mm in 24%, 32 mm in 36%, and ≥ 36 mm in 21%.
288 THAs (4.8%) dislocated. Younger (1st quartile, ≤ 41 years) patient age (odds ratio [OR] 1.45 CI [95% confidence interval] 1.02-2.07 vs. 2nd quartile), higher BMI (OR 1.05, CI 1.02-1.08 per 1), posterior approach (OR 3.33, CI 1.96-5.56 vs. anterior or anterolateral approach, OR 2.27 CI 1.59-3.23 vs. lateral approach), and smaller heads were identified as risk factors. However, ≥ 36-mm heads were not different from 32-mm heads (OR 1.06 CI 0.69-1.63).
Risk factors associated with dislocation were younger patient age, higher BMI, posterior approach, and smaller heads; however, 32-mm heads were large enough to reduce dislocation.
与骨关节炎患者相比,非创伤性股骨头坏死(ONFH)患者在初次全髋关节置换术(THA)后脱位风险更高。目前尚不清楚应使用多大尺寸的假体头来降低脱位风险。一项针对ONFH患者进行的THA的全国性多中心随访队列研究旨在评估与脱位相关的风险因素,以及较大尺寸的假体头是否能降低脱位风险。
采用多变量逻辑回归模型分析了1996年至2022年间为ONFH患者进行的5983例THA中与脱位相关的因素,中位随访时间为7.1(0.5 - 27)年。手术时患者年龄中位数为52岁,体重指数(BMI)中位数为22.9。59%的患者采用后入路。假体头直径为22mm的占4%,26mm的占15%,28mm的占24%,32mm的占36%,≥36mm的占21%。
288例THA(4.8%)发生脱位。较年轻(第一四分位数,≤41岁)的患者年龄(比值比[OR]1.45,95%置信区间[CI]1.02 - 2.07,与第二四分位数相比)、较高的BMI(每增加1,OR 1.05,CI 1.02 - 1.08)、后入路(与前入路或前外侧入路相比,OR 3.33,CI 1.96 - 5.56;与外侧入路相比,OR 2.27,CI 1.59 - 3.23)以及较小尺寸的假体头被确定为风险因素。然而,≥36mm的假体头与32mm的假体头相比并无差异(OR 1.06,CI 0.69 - 1.63)。
与脱位相关的风险因素包括较年轻的患者年龄、较高的BMI、后入路和较小尺寸的假体头;然而,32mm的假体头足以降低脱位风险。