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股骨头非创伤性骨坏死全髋关节置换术后脱位的相关因素:一项对5983例髋关节的多中心队列研究。

Factors associated with dislocation after total hip arthroplasties performed for nontraumatic osteonecrosis of the femoral head: a multicenter cohort study of 5,983 hips.

作者信息

Kobayashi Seneki, Sugano Nobuhiko, Ando Wataru, Fukushima Wakaba, Kondo Kyoko, Sakai Takashi

机构信息

The Investigation Committee on Osteonecrosis of the Femoral Head under the Ministry of Health, Labour and Welfare, Tokyo; Department of Orthopaedic Surgery, Suwa Red Cross Hospital, Suwa, Japan.

The Investigation Committee on Osteonecrosis of the Femoral Head under the Ministry of Health, Labour and Welfare, Tokyo; epartment of Orthopaedic Medical Engineering, Osaka University Graduate School of Medicine, Suita, Japan.

出版信息

Acta Orthop. 2025 Apr 17;96:348-355. doi: 10.2340/17453674.2025.43473.

Abstract

BACKGROUND AND PURPOSE

Nontraumatic osteonecrosis of the femoral head (ONFH) patients are at a higher dislocation risk after primary total hip arthroplasties (THAs) than osteoarthrosis patients. It has not been clear how large prosthetic heads should be to reduce dislocation. A nationwide multicenter follow-up cohort study of THAs performed for ONFH aimed to evaluate risk factors associated with dislocation and whether larger head size could reduce the dislocation risk.

METHODS

A multivariable logistic regression model analyzed factors associated with dislocation in 5,983 THAs performed for ONFH between 1996 and 2022 with a median of 7.1 (0.5-27)-year follow-up. Patient age at surgery was 52 years and BMI was 22.9, as medians. A posterior approach was employed in 59%. The head diameter was 22 mm in 4%, 26 mm in 15%, 28 mm in 24%, 32 mm in 36%, and ≥ 36 mm in 21%.

RESULTS

288 THAs (4.8%) dislocated. Younger (1st quartile, ≤ 41 years) patient age (odds ratio [OR] 1.45 CI [95% confidence interval] 1.02-2.07 vs. 2nd quartile), higher BMI (OR 1.05, CI 1.02-1.08 per 1), posterior approach (OR 3.33, CI 1.96-5.56 vs. anterior or anterolateral approach, OR 2.27 CI 1.59-3.23 vs. lateral approach), and smaller heads were identified as risk factors. However, ≥ 36-mm heads were not different from 32-mm heads (OR 1.06 CI 0.69-1.63).

CONCLUSION

Risk factors associated with dislocation were younger patient age, higher BMI, posterior approach, and smaller heads; however, 32-mm heads were large enough to reduce dislocation.

摘要

背景与目的

与骨关节炎患者相比,非创伤性股骨头坏死(ONFH)患者在初次全髋关节置换术(THA)后脱位风险更高。目前尚不清楚应使用多大尺寸的假体头来降低脱位风险。一项针对ONFH患者进行的THA的全国性多中心随访队列研究旨在评估与脱位相关的风险因素,以及较大尺寸的假体头是否能降低脱位风险。

方法

采用多变量逻辑回归模型分析了1996年至2022年间为ONFH患者进行的5983例THA中与脱位相关的因素,中位随访时间为7.1(0.5 - 27)年。手术时患者年龄中位数为52岁,体重指数(BMI)中位数为22.9。59%的患者采用后入路。假体头直径为22mm的占4%,26mm的占15%,28mm的占24%,32mm的占36%,≥36mm的占21%。

结果

288例THA(4.8%)发生脱位。较年轻(第一四分位数,≤41岁)的患者年龄(比值比[OR]1.45,95%置信区间[CI]1.02 - 2.07,与第二四分位数相比)、较高的BMI(每增加1,OR 1.05,CI 1.02 - 1.08)、后入路(与前入路或前外侧入路相比,OR 3.33,CI 1.96 - 5.56;与外侧入路相比,OR 2.27,CI 1.59 - 3.23)以及较小尺寸的假体头被确定为风险因素。然而,≥36mm的假体头与32mm的假体头相比并无差异(OR 1.06,CI 0.69 - 1.63)。

结论

与脱位相关的风险因素包括较年轻的患者年龄、较高的BMI、后入路和较小尺寸的假体头;然而,32mm的假体头足以降低脱位风险。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/69b4/12006036/3aaf2a2429f2/ActaO-96-43473-g001.jpg

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