Suto Ryuichiro, Nakafuji Yoshito, Mochizuki Kyoko, Oka Kazunori, Jinbo Mitsutaka, Chiba Fumihiro, Moriuchi Hiroki, Ikeda Yuji, Nawata Sumihiko, Zempo Nobuya, Kurata Satoru, Nakayasu Kiyoshi, Esato Kensuke, Kamei Toshiaki
Dept. of Surgery, Yamaguchi Prefecture Hospital.
Gan To Kagaku Ryoho. 2003 Dec;30(13):2119-23.
We report 2 cases in which the weekly administration of paclitaxel proved to be effective for patients with scirrhous gastric cancer who underwent a curability C operation. Weekly paclitaxel therapy was observed to effectively treat peritoneal and retroperitoneal dissemination. After this treatment the tumor markers decreased markedly. This weekly paclitaxel therapy was observed to cause no adverse effects, and thanks to the treatment the patients were able to consume normal meals. These patients could also be sufficiently treated as outpatients. Weekly paclitaxel therapy is thus considered to be effective for the treatment of advanced scirrhous gastric cancer with peritoneal and retroperitoneal dissemination.
我们报告了2例病例，其中每周给予紫杉醇治疗对接受根治性C手术的硬癌型胃癌患者有效。观察发现，每周一次的紫杉醇治疗可有效治疗腹膜和腹膜后转移。经过这种治疗后，肿瘤标志物明显下降。观察到每周一次的紫杉醇治疗未引起不良反应，并且由于该治疗，患者能够正常进食。这些患者也可以作为门诊患者得到充分治疗。因此，每周一次的紫杉醇治疗被认为对治疗伴有腹膜和腹膜后转移的晚期硬癌型胃癌有效。
