Seregin G I, Len'kova N A, Vornovitskii E G
Department of Anesthesiology and Reanimatology No. 2, N. N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, Moscow.
Bull Exp Biol Med. 2003 Oct;136(4):392-5. doi: 10.1023/b:bebm.0000010961.14550.b9.
We studied the distribution of main frequencies of spontaneous activity (in the range of 2-4 cycles/min) of the stomach and large intestine in healthy individuals and patients with stomach and colon cancer before and after gastrectomy and resection or total colectomy. The rhythm was recorded noninvasively (from body surface) with Ag/AgCl electrodes connected to a 3-channel portable electrogastrograph. We determined general peculiarities of rhythm formation in the stomach and large intestine in healthy individuals on an empty stomach and after mixed feeding and evaluated changes in spontaneous activity in patients with stomach and colon cancer before and after gastrectomy, resection, or total colectomy. Rhythmic activity of the stomach was coordinated with that of the large intestine in healthy individuals, but not in patients with tumors before the start of specific therapy. Multichannel cutaneous electrogastroenterography and recording of spontaneous electrical activity in the epigastric and perianal regions reflect functional relationships between the stomach and large intestine.
我们研究了健康个体以及胃癌和结肠癌患者在胃切除、结肠切除或全结肠切除术前、后的胃和大肠自发活动的主频分布（范围为每分钟2 - 4个周期）。通过连接到三通道便携式胃电图仪的Ag/AgCl电极从体表无创记录节律。我们确定了健康个体空腹和混合进食后胃和大肠节律形成的一般特点，并评估了胃癌和结肠癌患者在胃切除、结肠切除或全结肠切除术前、后的自发活动变化。在健康个体中，胃的节律活动与大肠的节律活动相协调，但在开始特异性治疗前的肿瘤患者中并非如此。多通道皮肤胃肠电图以及上腹部和肛周区域自发电活动的记录反映了胃和大肠之间的功能关系。
