Burgoon P W, Lindberg P T, Gillette M U
B107 Chemical and Life Sciences Laboratory, Department of Cell and Structural Biology, University of Illinois at Urbana-Champaign, 601 S. Goodwin Avenue, Urbana, IL 61801, USA.
J Comp Physiol A Neuroethol Sens Neural Behav Physiol. 2004 Feb;190(2):167-71. doi: 10.1007/s00359-003-0486-z. Epub 2004 Jan 9.
Although spontaneous neural firing in the mammalian suprachiasmatic nucleus is accepted to peak once during mid-subjective day, dual activity peaks have been reported in horizontal brain slices taken from hamsters. These two peaks were interpreted as new evidence for the theory of dual circadian oscillators and raised the expectation that such activity would be found in other circadian model systems. We examined hamster, mouse, and rat slices in both coronal and horizontal planes and found a second peak of activity only in hamster horizontal preparations. This raises interesting questions about the relative circadian physiology of these important experimental animals.
虽然哺乳动物视交叉上核中的自发神经放电被认为在主观日中期达到一次峰值，但在从仓鼠获取的水平脑切片中已报道存在双重活动峰值。这两个峰值被解释为双生物钟振荡器理论的新证据，并引发了这样的期望，即这种活动会在其他生物钟模型系统中被发现。我们在冠状面和水平面检查了仓鼠、小鼠和大鼠的脑切片，结果发现仅在仓鼠的水平标本中存在第二个活动峰值。这就引发了关于这些重要实验动物相对生物钟生理学的有趣问题。
