Tarsa Monika, Zuchowski Grzegorz, Bojarşki Jacek
Department of Organic Chemistry, Medical College, Jagiellonian University, 9 Medyczna Str., 30-688 Kraków, Poland.
Acta Pol Pharm. 2003 Jul-Aug;60(4):247-52.
Kinetics of hydrolysis of S-methyl-2-thiophenobarbital in aqueous solutions was investigated using the UV spectroscopic method within the pH range 1.5-12.9 at 60 degrees C. Chromatography was used to separate and isolate the products of hydrolysis of this compound and its N-methyl isomer. The products were identified by spectroscopic methods and the course of hydrolysis of both isomers were compared.
采用紫外光谱法，在60℃、pH值为1.5至12.9的范围内，研究了S-甲基-2-硫代苯巴比妥在水溶液中的水解动力学。利用色谱法分离并分离出该化合物及其N-甲基异构体的水解产物。通过光谱方法鉴定产物，并比较了两种异构体的水解过程。
