Deltenre P, Colin C, Dachy B, Mansbach A L
Université Libre de Bruxelles, Clinique de Neurophysiologie & Institut d'Implant Cochléaire de l'ULB, CHU Brugmann, Bruxelles, Belgium.
Acta Otorhinolaryngol Belg. 2003;57(4):253-66.
This paper presents an overview of the use of EPs in the assessment of the CANS. Emphasis is laid on recent developments and research efforts centered on appraising how the auditory neural code is processed by the central pathways. It is shown how, in addition to their classical site-of-lesion testing role, EPs can, especially when combined with ecological (mostly speech-like) stimuli, yield highly valuable information on the neurophysiological processes leading to the perception of auditory objects as well as speech. Special space is devoted to the Mismatch Negativity that currently provides the only objective measure of the accuracy with which the CANS detects auditory and phonetic contrasts.
本文概述了事件相关电位(EPs)在中枢听觉神经系统(CANS)评估中的应用。重点介绍了围绕评估中枢通路如何处理听觉神经编码的最新进展和研究成果。文中展示了,除了其经典的病变部位检测作用外,事件相关电位,特别是与生态(主要是类似语音的)刺激相结合时,能提供关于导致听觉对象以及语音感知的神经生理过程的极具价值的信息。文中特别介绍了失匹配负波,它目前是中枢听觉神经系统检测听觉和语音对比准确性的唯一客观测量指标。