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左心室肥厚且射血分数正常的患者出现左心室射血分数降低的情况。

Development of a depressed left ventricular ejection fraction in patients with left ventricular hypertrophy and a normal ejection fraction.

作者信息

Rame J Eduardo, Ramilo Marlon, Spencer Nali, Blewett Christopher, Mehta Sameer K, Dries Daniel L, Drazner Mark H

机构信息

Cardiovascular Branch, National Heart, Lung, and Blood Institute, Bethesda, Maryland, USA.

出版信息

Am J Cardiol. 2004 Jan 15;93(2):234-7. doi: 10.1016/j.amjcard.2003.09.050.

Abstract

The progression from concentric left ventricular (LV) hypertrophy to heart failure has not been well defined. Of 159 predominantly hypertensive African-American patients with LV hypertrophy and a normal ejection fraction (EF), 28 (18%) developed a reduced EF after a median follow-up of approximately 4 years. Risk factors for this outcome included a history of coronary artery disease, pulmonary edema seen on a chest x-ray, or a subsequent myocardial infarction.

摘要

从同心性左心室肥厚发展至心力衰竭的过程尚未完全明确。在159例主要为高血压的非裔美国左心室肥厚患者中,其射血分数(EF)正常,经过约4年的中位随访后,28例(18%)出现了EF降低。这一结果的危险因素包括冠状动脉疾病史、胸部X线显示的肺水肿或随后发生的心肌梗死。

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