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Pharmacological and toxicological significance of brain cytochromes P450.

作者信息

Ravindranath V

机构信息

Department of Neurochemistry, National Institute of Mental Health And Neurosciences, Hosur Road, Bangalore 560 029, India.

出版信息

Neurotox Res. 2001 Aug;3(4):321-8. doi: 10.1007/BF03033193.

DOI:10.1007/BF03033193
PMID:14715462
Abstract
摘要

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本文引用的文献

1
Cytochrome P4502E (CYP2E) in brain: constitutive expression, induction by ethanol and localization by fluorescence in situ hybridization.大脑中的细胞色素P4502E(CYP2E):组成型表达、乙醇诱导及荧光原位杂交定位
Arch Biochem Biophys. 2000 Jan 1;373(1):23-34. doi: 10.1006/abbi.1999.1477.
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Expression of multiple forms of cytochrome P450 and associated mono-oxygenase activities in rat brain regions.大鼠脑区中多种细胞色素P450形式的表达及相关单加氧酶活性
Biochem Pharmacol. 1998 Aug 1;56(3):371-5. doi: 10.1016/s0006-2952(98)00036-7.
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Genomic cloning and protein expression of a novel rat brain cytochrome P-450 CYP2D18* catalyzing imipramine N-demethylation.
一种催化丙咪嗪N-去甲基化的新型大鼠脑细胞色素P-450 CYP2D18*的基因组克隆与蛋白表达。
J Biol Chem. 1996 Nov 8;271(45):28176-80. doi: 10.1074/jbc.271.45.28176.
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Xenobiotic metabolism in brain.脑内的外源性物质代谢
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Expression analysis of the mixed function oxidase system in rat brain by the polymerase chain reaction.用聚合酶链反应分析大鼠脑中混合功能氧化酶系统的表达
Mol Cell Biochem. 1993 Mar 24;120(2):171-9. doi: 10.1007/BF00926090.
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The chronic administration of nicotine induces cytochrome P450 in rat brain.
J Neurochem. 1993 May;60(5):1941-4. doi: 10.1111/j.1471-4159.1993.tb13424.x.
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Induction of brain cytochrome P-450IIE1 by chronic ethanol treatment.慢性乙醇处理对脑细胞色素P-450IIE1的诱导作用。
Brain Res. 1993 Jan 22;601(1-2):279-85. doi: 10.1016/0006-8993(93)91721-4.
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Advances in our understanding of the mechanisms of the neurotoxicity of MPTP and related compounds.我们对MPTP及相关化合物神经毒性机制认识的进展。
J Neurochem. 1993 Oct;61(4):1191-206. doi: 10.1111/j.1471-4159.1993.tb13610.x.
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Progress in psychiatry (1).
N Engl J Med. 1993 Aug 19;329(8):552-60. doi: 10.1056/NEJM199308193290808.
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Regional distribution and expression modulation of cytochrome P-450 and epoxide hydrolase mRNAs in the rat brain.细胞色素P-450和环氧水解酶mRNA在大鼠脑中的区域分布及表达调控
Mol Pharmacol. 1993 Nov;44(5):990-6.