Tønnesen H
Alcohol Research Center, Copenhagen.
Acta Psychiatr Scand Suppl. 1992;369:67-71.
Alcohol intake influences several physiological functions, including the haemostatic system, the cellular immune defence and the cardiac function, but to a different degree depending on the drinking habits. Restoration of these functions after withdrawal seems time related. The haemostatic imbalance normalizes within two or three weeks of soberness while the immune system requires about two months to recover. Recent studies have showed very increased postoperative morbidity after surgery in alcohol abusers, which may be explained by alcohol-induced physiological dysfunctions. Theoretically, two months of abstinence before a surgical procedure would diminish the increased postoperative morbidity among alcohol abusers. However, further investigation is necessary to establish a clinical effect of preoperative withdrawal from alcohol.
酒精摄入会影响多种生理功能，包括止血系统、细胞免疫防御和心脏功能，但根据饮酒习惯的不同，影响程度也有所不同。戒酒之后这些功能的恢复似乎与时间有关。止血失衡在戒酒两到三周内恢复正常，而免疫系统则需要大约两个月才能恢复。最近的研究表明，酗酒者术后发病率大幅增加，这可能是由酒精引起的生理功能障碍所致。理论上，手术前戒酒两个月会降低酗酒者术后发病率的增加。然而，有必要进行进一步调查，以确定术前戒酒的临床效果。
