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改善结核性脑膜炎的细菌学诊断

Improving the bacteriological diagnosis of tuberculous meningitis.

作者信息

Thwaites Guy E, Chau Tran Thi Hong, Farrar Jeremy J

机构信息

Oxford University Clinical Research Unit, Hospital for Tropical Diseases, Ho Chi Minh City, Vietnam.

出版信息

J Clin Microbiol. 2004 Jan;42(1):378-9. doi: 10.1128/JCM.42.1.378-379.2004.

DOI:10.1128/JCM.42.1.378-379.2004
PMID:14715783
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC321694/
Abstract

We made a bacteriological diagnosis of tuberculous meningitis in 107 of 132 (81%) adults with clinical tuberculous meningitis: acid-fast bacilli were seen in 77 of 132 (58%) and cultured from 94 of 132 (71%). Volume of cerebrospinal fluid, duration of symptoms, cerebrospinal fluid neutrophils, lactate, and glucose were all independently associated with bacteriological confirmation.

摘要

在132例临床诊断为结核性脑膜炎的成人患者中，我们对其中107例（81%）做出了结核性脑膜炎的细菌学诊断：132例中有77例（58%）发现抗酸杆菌，132例中有94例（71%）培养出结核杆菌。脑脊液量、症状持续时间、脑脊液中性粒细胞、乳酸和葡萄糖水平均与细菌学确诊独立相关。

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本文引用的文献

1
Pathophysiology and prognosis in vietnamese adults with tuberculous meningitis.越南成年结核性脑膜炎患者的病理生理学与预后
J Infect Dis. 2003 Oct 15;188(8):1105-15. doi: 10.1086/378642. Epub 2003 Oct 2.
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The bacteriological diagnosis of tuberculous meningitis.结核性脑膜炎的细菌学诊断
J Clin Pathol. 1953 Aug;6(3):241-2. doi: 10.1136/jcp.6.3.241.
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Diagnosis of adult tuberculous meningitis by use of clinical and laboratory features.利用临床和实验室特征诊断成人结核性脑膜炎。
Lancet. 2002 Oct 26;360(9342):1287-92. doi: 10.1016/s0140-6736(02)11318-3.
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Steep increase in HIV prevalence among tuberculosis patients in Ho Chi Minh City.胡志明市结核病患者中艾滋病毒感染率急剧上升。
AIDS. 2002 Apr 12;16(6):931-2. doi: 10.1097/00002030-200204120-00016.
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Tuberculosis of the central nervous system.中枢神经系统结核
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Tuberculous meningitis.结核性脑膜炎
JAMA. 1979 Jan 19;241(3):264-8.