Insanov A B, Gadzhiev F S, Kiazimova L G, Feizullaeva N A
Azerbaijan NII of Phthisiology and Pulmonology, Baku.
Probl Tuberk. 1996(5):25-8.
An examination was made of 133 children and 89 adults, aged 3 to 60 years, who had admitted for suspected tuberculous meningitis. The diagnosis of tuberculous meningitis was established in 113 children and 79 adults. In the remaining 20 ill children and 10 adult patients, tuberculous etiology of the disease was rejected. After puncture, spinal fluid was examined by three methods, bacretioscopy, cultivation, and biological assay. Bacterioscopy detected Mycobacteria tuberculosis in 5.3 and 2.5% of ill children and adults, respectively. Types of M. tuberculosis were isolated more frequently in children (n = 66 (58.4%)) than in adults (n = 22 (27.9%)) by bacteriology and in 39 (34.5%) and 15 (30.0%) adults by biological assay. The spinal fluid much more frequently displayed changed forms (L forms) of M. tuberculosis than bacterial ones. They were isolated in 62 (54.9%) and 59 (74.6%) adults by cultivation. On the whole, spinal fluid cultivation for L forms of M. tuberculosis allowed the total detection percentages for an etiological factor to be increased in children and adults, who both suffered from tuberculous meningitis, they accounted for 87.6 and 87.3%, respectively.
对133名3至60岁因疑似结核性脑膜炎入院的儿童和89名成人进行了检查。确诊为结核性脑膜炎的儿童有113名，成人有79名。其余20名患病儿童和10名成年患者排除了结核病因。穿刺后，通过三种方法检查脑脊液：细菌镜检、培养和生物测定。细菌镜检在患病儿童和成人中分别检测到结核分枝杆菌的比例为5.3%和2.5%。通过细菌学方法，结核分枝杆菌的类型在儿童中（n = 66 (58.4%)）比在成人中（n = 22 (27.9%)）更频繁地分离出来；通过生物测定，在成人中分别为39例（34.5%）和15例（30.0%）。脑脊液中结核分枝杆菌的L型比细菌型更频繁地出现。通过培养，在成人中分别有62例（54.9%）和59例（74.6%）分离出L型。总体而言，对结核分枝杆菌L型进行脑脊液培养可提高患结核性脑膜炎的儿童和成人病因因素的总检测率，分别占87.6%和87.3%。
