Kendall Katherine A, Louie Samuel
Department of Otolaryngology, University of California, Davis, Davis, CA, USA.
Clin Rev Allergy Immunol. 2003 Dec;25(3):221-31. doi: 10.1385/CRIAI:25:3:221.
Vocal Fold Dysfunction is a syndrome characterized by abnormal adduction of the focal folds during inspiration and is the cause of a wide spectrum of clinical manifestations ranging from mild inspiratory stridor to an inability to move any air. Patients present with varying degrees of intermittent respiratory difficulty, the most severe caused by intense laryngospasm. Distinguishing Vocal Fold Dysfunction from Refractory Asthma is important to avoid unnecessary pharmacotherapy and intubation. The diagnosis of Vocal Fold Dysfunction can only be made with certainty by flexible fiberoptic laryngoscopy while the patient is symptomatic. Pulmonary function studies and a lack of response to bronchodilators may provide clues to the diagnosis. Most patients with the condition can be managed by speech therapy and the use of breathing strategies that eliminate the abnormal vocal fold movement. Chronic laryngeal irritation may be a trigger for Vocal Fold Dysfunction and conditions such as laryngopharyngeal reflux disease should be aggressively managed in this patient population.
声带功能障碍是一种以吸气时声带异常内收为特征的综合征，是导致从轻度吸气性喘鸣到无法通气等一系列临床表现的原因。患者表现出不同程度的间歇性呼吸困难，最严重的情况是由强烈的喉痉挛引起的。将声带功能障碍与难治性哮喘区分开来对于避免不必要的药物治疗和插管很重要。声带功能障碍的诊断只能在患者出现症状时通过软性纤维喉镜检查才能确定。肺功能研究以及对支气管扩张剂缺乏反应可能为诊断提供线索。大多数患有这种疾病的患者可以通过言语治疗和使用消除异常声带运动的呼吸策略来进行管理。慢性喉部刺激可能是声带功能障碍的一个触发因素，对于这类患者群体，应积极治疗诸如喉咽反流病等疾病。
