Chatterjee S, Savant V V, Stavrou P
Birmingham and Midland Eye Centre, UK.
Eye (Lond). 2004 Jun;18(6):575-9. doi: 10.1038/sj.eye.6700747.
To determine diabetic retinopathy or maculopathy progression and visual outcome following phacoemulsification in South-Asian and Afro-Caribbean patients with diabetes.
Review of notes of patients with type II diabetes undergoing phacoemulsification by one surgeon. The inclusion criteria were: (a) South-Asian or Afro-Caribbean ethnicity, (b) monocular cases with a minimum postoperative follow-up of 6 months, and (c) binocular cases with an interval of at least 6 months between the operation in the two eyes. The nonoperated eye was used as control. The development or progression of diabetic retinopathy or maculopathy and final visual acuity were recorded.
In all, 30 diabetic patients were included. There were 19 South-Asians (Pakistani, Indian, and Bangladeshi) and 11 Afro-Caribbeans. The mean (+/-SD) age was 68.9 (+/-10) years. Retinopathy or maculopathy progression was noted in seven patients (23.4%), two South-Asians, and five Afro-Caribbeans. There was no significant difference in the number of operated and fellow eyes whose retinopathy or maculopathy progressed postoperatively. Progression of retinopathy or maculopathy occurred more often in Afro-Caribbeans compared to South-Asians (P=0.02, logistic regression analysis). The mean (+/-SD) postoperative follow-up was 12.4 (+/-6.5) months. Visual acuity improved by at least two or more Snellen lines in 19 eyes (63.3%); 26 eyes (86.7%) achieved a final visual acuity of at least 6/12.
Afro-Caribbeans may be at a higher risk of progression of retinopathy or maculopathy after phacoemulsification.
确定南亚和非洲加勒比裔糖尿病患者白内障超声乳化术后糖尿病视网膜病变或黄斑病变的进展情况及视力转归。
回顾由一名外科医生为II型糖尿病患者实施白内障超声乳化手术的病历。纳入标准为：（a）南亚或非洲加勒比裔；（b）单眼病例，术后至少随访6个月；（c）双眼病例，两眼手术间隔至少6个月。未手术眼作为对照。记录糖尿病视网膜病变或黄斑病变的发生或进展情况以及最终视力。
共纳入30例糖尿病患者。其中19例为南亚人（巴基斯坦人、印度人和孟加拉国人），11例为非洲加勒比裔。平均（±标准差）年龄为68.9（±10）岁。7例患者（23.4%）出现视网膜病变或黄斑病变进展，其中2例为南亚人，5例为非洲加勒比裔。术后视网膜病变或黄斑病变进展的手术眼和对侧眼数量无显著差异。与南亚人相比，非洲加勒比裔视网膜病变或黄斑病变进展更为常见（P = 0.02，逻辑回归分析）。术后平均（±标准差）随访时间为12.4（±6.5）个月。19只眼（63.3%）视力至少提高了两行或更多Snellen视力表行数；26只眼（86.7%）最终视力至少达到6/12。
非洲加勒比裔患者白内障超声乳化术后视网膜病变或黄斑病变进展的风险可能更高。
