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在一个大型糖尿病患者队列中进行的超声乳化白内障手术:视力结果和预后因素。

Phacoemulsification cataract surgery in a large cohort of diabetes patients: visual acuity outcomes and prognostic factors.

机构信息

Department of Ophthalmology, Glostrup Hospital, Capital Region and University of Copenhagen, Copenhagen, Denmark.

出版信息

J Cataract Refract Surg. 2011 Nov;37(11):2006-12. doi: 10.1016/j.jcrs.2011.05.030. Epub 2011 Sep 1.

DOI:10.1016/j.jcrs.2011.05.030
PMID:21889874
Abstract

PURPOSE

To assess visual acuity outcomes after phacoemulsification cataract surgery in a large population of diabetic patients with all degrees of diabetic retinopathy.

SETTING

Diabetology and ophthalmology unit, Copenhagen, Denmark.

DESIGN

Cohort study.

METHODS

This review of prospectively collected data comprised patients who had small-incision phacoemulsification cataract surgery between 1999 and 2008 (10 years) according to the Danish National Patient Registry.

RESULTS

Data of 7323 diabetic patients were reviewed. Of these patients, 285 had cataract surgery. The corrected distance visual acuity (CDVA) increased significantly after cataract surgery (P<.001; P<.05 in all diabetic retinopathy categories). The postoperative CDVA outcome was positively correlated with preoperative CDVA and negatively correlated with the degree of diabetic retinopathy and age (P<.001). Patients with a history of focal laser treatment for clinically significant macular edema had a higher risk for not gaining from cataract surgery (P=.04; relative risk, 1.6). In post hoc analysis, the proportion of patients in the cohort without diabetic retinopathy appeared to increase the year before cataract surgery (P=.03) and decrease the year after cataract surgery (P<.001).

CONCLUSIONS

The CDVA increased significantly after phacoemulsification cataract surgery in diabetic patients regardless of the degree of diabetic retinopathy. The apparent progression in diabetic retinopathy after modern cataract surgery seems to reflect the masking of low grades of diabetic retinopathy by preoperative lens opacities.

FINANCIAL DISCLOSURE

No author has a financial or proprietary interest in any material or method mentioned.

摘要

目的

评估所有糖尿病视网膜病变程度的糖尿病患者行超声乳化白内障吸除术后的视力结果。

设置

丹麦哥本哈根的糖尿病学和眼科单位。

设计

队列研究。

方法

这项前瞻性收集数据的回顾纳入了根据丹麦国家患者登记处于 1999 年至 2008 年(10 年)间行小切口超声乳化白内障吸除术的患者。

结果

共回顾了 7323 例糖尿病患者的数据。其中 285 例患者行白内障手术。白内障手术后校正距离视力(CDVA)显著提高(P<.001;所有糖尿病视网膜病变类别中 P<.05)。术后 CDVA 结果与术前 CDVA 呈正相关,与糖尿病视网膜病变程度和年龄呈负相关(P<.001)。有临床显著黄斑水肿的局灶性激光治疗史的患者,白内障手术获益的风险更高(P=.04;相对风险 1.6)。事后分析中,白内障手术前一年,队列中无糖尿病视网膜病变的患者比例似乎增加(P=.03),而手术后一年则减少(P<.001)。

结论

无论糖尿病视网膜病变程度如何,超声乳化白内障吸除术后 CDVA 均显著提高。现代白内障手术后糖尿病视网膜病变的明显进展似乎反映了术前晶状体混浊掩盖了低等级的糖尿病视网膜病变。

利益披露

没有作者在任何提到的材料或方法中有财务或所有权利益。

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