Chadwick C, Marven S M, Vora A J
Paediatric Surgical Unit & Department of Paediatric Haematology, Sheffield Children's Hospital, Sheffield, UK.
Bone Marrow Transplant. 2004 Feb;33(4):451-3. doi: 10.1038/sj.bmt.1704370.
Bronchiolitis obliterans (BO) is a manifestation of chronic graft-versus-host disease (GVHD) after allogeneic haemopoietic stem cell transplantation. Complications associated with this include persistent air-leak syndromes such as pneumothorax. Many methods have been described for treating this condition, both surgical and nonsurgical. We describe an 8-year-old boy with acute lymphoblastic leukaemia complicated by chronic GVHD-related BO, and subsequent pneumothorax with persistent air leak, who was treated successfully with autologous blood pleurodesis.
闭塞性细支气管炎（BO）是异基因造血干细胞移植后慢性移植物抗宿主病（GVHD）的一种表现形式。与之相关的并发症包括持续性漏气综合征，如气胸。治疗这种病症的方法有很多，包括手术和非手术方法。我们描述了一名8岁男孩，患有急性淋巴细胞白血病并并发慢性GVHD相关的BO，随后出现气胸并伴有持续性漏气，他通过自体血胸膜固定术成功治愈。
