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内镜下括约肌切开术治疗胆总管结石后的长期症状

Long-term symptoms following endoscopic sphincterotomy for common bile duct stones.

作者信息

Macadam R C A, Goodall R J R

机构信息

Department of Surgery, Calderdale Royal Hospital, Salterhebble, Halifax, England HX3 OPW, United Kingdom.

出版信息

Surg Endosc. 2004 Mar;18(3):363-6. doi: 10.1007/s00464-002-9285-9. Epub 2004 Jan 14.

Abstract

BACKGROUND

Endoscopic sphincterotomy (ES) has an important role in the management of biliary stones. However, the long-term effects of free duodenobiliary reflux are not established, and it may lead to low-grade morbidity.

METHODS

We used a questionnaire survey to assess the prevalence of symptoms of biliary disorder in patients who had undergone endoscopic retrograde cholangio pancreatography (ERCP) and ES under the care of a single surgeon (R.J.R.G) between November 1993 and May 1998.

RESULTS

ES was carried out on 136 patients during this period. Current addresses were available for 94 patients, and 54 of them (57%) responded. Patients were surveyed a mean of 43 months after ES. Only 42.1% of patients denied having any symptoms. Nausea and pale stools were reported by 28% and 26% of patients, respectively, and nearly one-fifth of patients had symptoms suggestive of cholangitis. In addition, 18.5% of patients experienced one or more symptoms frequently.

CONCLUSION

Severe long-term symptoms are uncommon following ES; however, a significant minority of patients do suffer occasional symptoms that suggest biliary dysfunction.

摘要

背景

内镜下括约肌切开术(ES)在胆石症的治疗中具有重要作用。然而,十二指肠胆反流的长期影响尚未明确,且可能导致轻度发病。

方法

我们采用问卷调查的方式,评估了1993年11月至1998年5月期间在单一外科医生(R.J.R.G)照料下接受内镜逆行胰胆管造影术(ERCP)和ES的患者中胆道疾病症状的发生率。

结果

在此期间,对136例患者实施了ES。94例患者有当前住址,其中54例(57%)进行了回应。患者在ES后平均43个月接受调查。仅有42.1%的患者否认有任何症状。分别有28%和26%的患者报告有恶心和大便颜色变浅的症状,近五分之一的患者有提示胆管炎的症状。此外,18.5%的患者经常出现一种或多种症状。

结论

ES后出现严重长期症状的情况并不常见;然而,相当一部分患者确实偶尔会出现提示胆道功能障碍的症状。

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