Hsu Chia-Chen, Wang Jun-Wen, Chen Chin-En, Lin Jui-Wei
Department of Orthopaedic Surgery, Chang Gung Memorial Hospital, Niaosung Shiang, Kaohsiung, Taiwan, ROC.
Chang Gung Med J. 2003 Oct;26(10):761-7.
Chondroblastomas of the bone are rare lesions. Most of these lesions can be successfully treated by curettage and bone grafting. However, a considerable rate of recurrence has been reported, especially in aggressive lesions. The purpose of this study was to report the results of 10 cases of chondroblastomas of the bone treated with curettage and high-speed burring.
Ten patients with histologically confirmed chondroblastoma of the bone were treated with curettage and high-speed burring between October 1991 and August 2000. There were 7 men and 3 women with an average age of 18.9 (range, 12 to 30) years. Radiographically, 3 were classified as having aggressive lesions, and 7 were classified as having non-aggressive ones. For treatment, 8 of them had defects packed with either bone grafts or bone substitutes; 1 defect was packed with bone cement; and the other was left alone because the lesion was small.
At an average follow-up period of 62 (range, 8 to 112) months, all patients had painless, normal function of the affected limb without local recurrence or distant metastasis. Complete healing of the lesion was seen in 8 patients including the one without a bone graft. The lesion in 1 patient who had received bone cement remained unchanged radiographically. One patient experienced incomplete healing of the lesion, which was caused by inadequate packing of the bone substitute.
Curettage and high-speed burring represent an effective method for the treatment of chondroblastoma of the bone whether in the non-aggressive or aggressive stage.
骨软骨母细胞瘤是一种罕见的病变。这些病变大多可通过刮除术和植骨成功治疗。然而，据报道复发率相当高，尤其是在侵袭性病变中。本研究的目的是报告10例采用刮除术和高速磨钻治疗的骨软骨母细胞瘤的结果。
1991年10月至2000年8月期间，对10例经组织学确诊的骨软骨母细胞瘤患者采用刮除术和高速磨钻进行治疗。其中男性7例，女性3例，平均年龄18.9岁（范围12至30岁）。影像学上，3例被分类为侵袭性病变，7例为非侵袭性病变。治疗时，8例患者的缺损用骨移植材料或骨替代物填充；1例缺损用骨水泥填充；另1例因病变较小未作处理。
平均随访62个月（范围8至112个月），所有患者患侧肢体无痛，功能正常，无局部复发或远处转移。8例患者包括1例未植骨者病变完全愈合。1例接受骨水泥治疗的患者病变在影像学上无变化。1例患者病变愈合不完全，原因是骨替代物填充不足。
刮除术和高速磨钻是治疗骨软骨母细胞瘤的有效方法，无论其处于非侵袭性还是侵袭性阶段。
