Gentlesk Philip J, Markwood Thor T, Atwood J Edwin
Cardiology Service, Walter Reed Army Medical Center, Washington, DC 20307-5001, USA.
Chest. 2004 Jan;125(1):297-301. doi: 10.1378/chest.125.1.297.
Chronotropic incompetence (CI) is the inability of heart rate response to meet metabolic demand. CI is associated with sinus node dysfunction, atrial fibrillation, or structural heart disease, and can lead to functional impairment. We report the case of a 34-year-old man with CI secondary to sinus node dysfunction who demonstrated significant improvement in functional capacity with rate-responsive pacing. Therapy for CI should be guided by the treatment of the underlying cause with consideration for rate-responsive pacing in symptomatic patients. The prognosis of CI is variable and dependent on underlying etiology.
变时性功能不全（CI）是指心率反应无法满足代谢需求的情况。CI与窦房结功能障碍、心房颤动或结构性心脏病相关，并可导致功能损害。我们报告了一例34岁患有继发于窦房结功能障碍的CI男性患者，其通过频率应答性起搏在功能能力方面有显著改善。CI的治疗应以治疗潜在病因为指导，并考虑对有症状患者进行频率应答性起搏。CI的预后各不相同，取决于潜在病因。
