口腔鳞状细胞癌治疗后甲状旁腺激素相关肽诱导的高钙血症

Hypercalcemia induced by parathyroid hormone-related peptide after treatment of squamous cell carcinoma of oral cavity.

作者信息

Ansari K, Clerk A, Patel M H, Sainani Anjana, Shastry P S R K, Advani S H

机构信息

Department of Critical Care, Jaslok Hospital and Research Centre, Mumbai.

出版信息

J Assoc Physicians India. 2003 Oct;51:1023-4.

PMID:14719600

Abstract

Squamous cell carcinoma of the head and neck is a rare cause of humoral hypercalcemia of malignancy. This paraneoplastic syndrome is usually one of the presenting symptoms of the disease. We report a case of squamous cell carcinoma of the oral cavity that presumably elaborated parathyroid hormone-related peptide (PTH-rP) and caused hypercalcemia only after radiotherapy and chemotherapy.

摘要

头颈部鳞状细胞癌是恶性肿瘤性体液性高钙血症的罕见病因。这种副肿瘤综合征通常是该疾病的首发症状之一。我们报告一例口腔鳞状细胞癌病例，该病例可能分泌甲状旁腺激素相关肽（PTH-rP），且仅在放疗和化疗后才导致高钙血症。