Dooley Patrick W, Bhardwaj V Ravi, Rayner David M, Corkum Paul B
Steacie Institute for Molecular Sciences, National Research Council of Canada, Ottawa, Ontario, K1A 0R6, Canada.
Anal Chem. 2004 Jan 15;76(2):262-6. doi: 10.1021/ac034621x.
We demonstrate that using intense femtosecond laser pulses to optically time ion flight can lead to a miniature time-of-flight mass spectrometer. After laser ionization, the molecular ion is accelerated by a static electric field and detected using a second, delayed laser pulse. The relative positions of the two laser foci determine the ion flight distance while the time separation of the laser pulses fixes the ion flight time. We mass-resolve CS(2) or C(6)H(6) isotopes after a flight distance of 360 microm using either double ionization or Coulomb explosion detection.
我们证明，使用高强度飞秒激光脉冲对离子飞行进行光学计时可导致产生微型飞行时间质谱仪。激光电离后，分子离子由静电场加速，并使用第二个延迟激光脉冲进行检测。两个激光焦点的相对位置决定离子飞行距离，而激光脉冲的时间间隔确定离子飞行时间。我们使用双电离或库仑爆炸检测方法，在飞行距离为360微米后对CS₂或C₆H₆同位素进行了质量分辨。
