肺基质重塑障碍
Disorders of lung matrix remodeling.
作者信息
Chapman Harold A
机构信息
Department of Medicine and Cardiovascular Research Institute, University of California at San Francisco, San Francisco, California 94143-0130, USA.
出版信息
J Clin Invest. 2004 Jan;113(2):148-57. doi: 10.1172/JCI20729.
Abstract
A set of lung diseases share the tendency for the development of progressive fibrosis ultimately leading to respiratory failure. This review examines the common pathogenetic features of these disorders in light of recent observations in both humans and animal models of disease, which reveal important pathways of lung matrix remodeling.
摘要
一组肺部疾病都有发展为进行性纤维化并最终导致呼吸衰竭的倾向。本综述根据在人类和动物疾病模型中的最新观察结果，探讨了这些疾病的共同发病机制，这些观察揭示了肺基质重塑的重要途径。
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