Le Querrec Agnès
Laboratoire d'hématologie, CHU Côte de Nacre, 14033 Caen.
Rev Prat. 2003 Nov 15;53(17):1900-5.
Venous thromboembolism has been reported to occur in 1 in 1,000 pregnancies, but is a leading cause of maternal mortality. The challenge is to identify women with risk factors for thromboembolism in pregnancy in order to initiate an appropriate treatment. The objective diagnosis of venous thromboembolism in pregnancy is crucial and have implications not only for management of the pregnancy but also for the choice of contraception and management of future pregnancies. Women with prior venous thrombosis, family history of thrombosis, or additional thrombophilic risks factors have to be evaluated in order to choice the best thromboprophylaxis for pregnancy and puerperium. However recommendations are of low grade (C) and in absence of large prospective studies, the therapeutic strategies are often empiric.
