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[使用根据脂质体技术方法修饰的磷脂治疗慢性肾功能不全患者]

[Using phospholipids modified according to the method of liposome technology in the treatment of patients with chronic renal insufficiency].

作者信息

Stepanova N M

出版信息

Lik Sprava. 2003 Oct-Nov(7):74-6.

PMID:14723142
Abstract

The article deals with treatment of chronic renal insufficiency, which is an issue of the day. 35 patients with chronic renal insufficiency (CRI) at I-II stages irrespective of primary nosological diagnosis have been investigated. It was the first time when LIPIN was prescribed at a total dose of 20 mg/kg to improve the methods of conservative therapy. The material presents dynamics of laboratory indices of renal function over treatment with LIPIN. It was established, that LIPIN statistically reliably decreases creatinine and urea level in patient's blood, absolutely brings down transmidase blood serum activity, reduce clinical presentations of uremic gastroenteropathy as well as improves general state of health.

摘要

本文论述了慢性肾功能不全的治疗,这是当今的一个重要问题。对35例处于I-II期的慢性肾功能不全(CRI)患者进行了研究,不论其原发性疾病诊断如何。首次以20mg/kg的总剂量使用LIPIN以改进保守治疗方法。材料展示了使用LIPIN治疗期间肾功能实验室指标的变化情况。已证实,LIPIN能使患者血液中的肌酐和尿素水平在统计学上显著降低,绝对降低血清转氨酶活性,减轻尿毒症性胃肠病的临床表现,并改善总体健康状况。

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