Phatak Mrunal S, Kurhade G A
Department of Physiology, Government Medical College, Nagpur 440 003.
Indian J Physiol Pharmacol. 2003 Jul;47(3):352-6.
A study of changes in lung function tests during pregnancy was undertaken in fifty pregnant women beginning from third month of gestation. Fifty nonpregnant age and height matched women formed the controls. Forced Vital Capacity (FVC), Timed Vital Capacity (FEV1), Inspiratory Capacity (IC), Expiratory Reserve Volume (ERV) and peak Expiratory Flow Rate (PEFR) were performed in each month of pregnancy. However ten subjects were not available for follow-up during postpartum period. Remaining forty women were divided into two groups of twenty each. Group I performed daily graded active exercises to strengthen the anterior abdominal wall muscles. Group II women did not perform any exercises. It was observed that the antenatal changes in percent FVC and FEV1 were insignificant, but the decline in ERV and PEFR were very highly significant (P < 0.001) and the increment in IC was significant (P < 0.05). In the postpartum period the percentage variation of values in group I was less than 5% from controls (P > 0.05) and in group II it was 15-20% from controls (P < 0.05), resulting in a significant variation in group II women as compared to the controls. It is concluded that there are adaptive changes in lung functions in the antenatal period. We stress the importance of regular graded active exercises in the postpartum period for the speedy recovery of these changes.
对50名孕妇从妊娠第三个月开始进行肺功能测试变化的研究。50名年龄和身高匹配的非孕妇作为对照。在妊娠的每个月都进行用力肺活量（FVC）、定时肺活量（FEV1）、吸气量（IC）、呼气储备量（ERV）和呼气峰值流速（PEFR）测试。然而，有10名受试者在产后期间无法进行随访。其余40名女性分为两组，每组20人。第一组每天进行分级主动锻炼以加强前腹壁肌肉。第二组女性不进行任何锻炼。观察到产前FVC和FEV1百分比的变化不显著，但ERV和PEFR的下降非常显著（P < 0.001），IC的增加显著（P < 0.05）。在产后期间，第一组数值与对照组的百分比变化小于5%（P > 0.05），第二组为15 - 20%（P < 0.05），导致第二组女性与对照组相比有显著差异。结论是产前肺功能有适应性变化。我们强调产后定期进行分级主动锻炼对这些变化快速恢复的重要性。
