镧系元素-PYBOX配合物催化腙的不对称氢氰化反应
Asymmetric hydrocyanation of hydrazones catalyzed by lanthanide--PYBOX complexes.
作者信息
Keith John M, Jacobsen Eric N
机构信息
Department of Chemistry and Chemical Biology, Harvard University, Cambridge, Massachusetts 02138, USA.
出版信息
Org Lett. 2004 Jan 22;6(2):153-5. doi: 10.1021/ol035844c.
PMID:14723516
Abstract
[reaction: see text] The asymmetric addition of HCN to hydrazones is catalyzed in high yield and good-to-excellent enantioselectivity by the easily prepared (PhPYBOX)ErCl3 complex. This constitutes the first example of asymmetric catalytic hydrocyanation of hydrazones.
摘要
[反应：见正文] 易于制备的(PhPYBOX)ErCl3配合物能高效催化腙的HCN不对称加成反应，对映选择性良好至优异。这是腙不对称催化氢氰化反应的首例。
Zotero 插件