Lee Peter J, MacLennan Allison, Naughton Norah N, O'Reilly Michael
Department of Anesthesiology, University of Michigan Health System, Ann Arbor, MI 48109-0048, USA.
J Clin Anesth. 2003 Dec;15(8):575-81. doi: 10.1016/j.jclinane.2003.03.006.
To determine if the majority of reintubations, a potentially preventable adverse event, were predominantly due to residual muscle relaxant effects, we analyzed our quality assurance database to identify the causes of reintubation.
Retrospective study.
University of Michigan Department of Anesthesiology Quality Assurance (QA) database.
We analyzed QA records from 152,939 anesthetic cases performed from 1994 to 1999 at our institution. Of these cases, 107,317 were performed with a general anesthetic. The medical record of each patient requiring reintubation was obtained and reviewed to determine the cause of the reintubation.
A total of 191 reintubation events were identified. One hundred twelve of the 191 (59%) reintubations were due to respiratory problems; 11 of the 191 (6%) reintubations were due to complications of neuromuscular blocking drug use. Other causes were unintentional extubation, surgical complication, endotracheal tube problems, and cardiac problems. One hundred five reintubations (105/191, 55%) occurred in the operating room and 86 (86/191, 45%) occurred in the postanesthesia care unit.
Respiratory complications were the most common cause of reintubation in the perioperative period. Complications related to the neuromuscular blocking drugs were the fourth most common cause of reintubation. More reintubations occurred in the operating room than the postanesthesia care unit. Muscle relaxant effect and opioid effect are rare causes of respiratory failure in the anesthetized patient in the immediate postoperative period.
为了确定再次插管这一潜在可预防的不良事件多数是否主要归因于残余肌松药效应,我们分析了我们的质量保证数据库以明确再次插管的原因。
回顾性研究。
密歇根大学麻醉学系质量保证(QA)数据库。
我们分析了1994年至1999年在我们机构进行的152,939例麻醉病例的QA记录。在这些病例中,107,317例采用全身麻醉。获取并审查了每位需要再次插管患者的病历,以确定再次插管的原因。
共识别出191例再次插管事件。191例中的112例(59%)再次插管是由于呼吸问题;191例中的11例(6%)再次插管是由于使用神经肌肉阻滞药物的并发症。其他原因包括意外拔管、手术并发症、气管内导管问题和心脏问题。105例再次插管(105/191,55%)发生在手术室,86例(86/191,45%)发生在麻醉后护理单元。
呼吸并发症是围手术期再次插管最常见的原因。与神经肌肉阻滞药物相关的并发症是再次插管的第四大常见原因。手术室发生的再次插管比麻醉后护理单元更多。在术后即刻,肌松药效应和阿片类药物效应是麻醉患者呼吸衰竭的罕见原因。