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动脉血气分析(ABG)能否为外科患者拔管提供安全保障?

Does Arterial Blood Gas (ABG) Provide a Safety Net for Extubation in Surgical Patients?

作者信息

Hazarika Amarjyoti, Singla Karan, Patel Gautham, Mahajan Varun, Kahlon Shubhkarman, Meena Shyam

机构信息

Anaesthesia and Intensive Care, Postgraduate Institute of Medical Education and Research, Chandigarh, IND.

出版信息

Cureus. 2023 Jan 9;15(1):e33561. doi: 10.7759/cureus.33561. eCollection 2023 Jan.

DOI:10.7759/cureus.33561
PMID:36779148
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9908425/
Abstract

Background Extubation has always been a critical aspect of anaesthesia. Guidelines and recommendations are in place for achieving successful extubation, but the risk of failure always persists. Through this study, we assess whether arterial blood gas (ABG) values taken intraoperatively help predict extubation success in the operation theatre. Materials and methods This was a prospective observational study for one year of extubated patients whose blood gas values were not within the normal range. The patients of age 18 years and above undergoing high-risk elective and emergency surgeries where at least one intraoperative arterial blood sample was taken for blood gas analysis were included. Apart from parameters of ABG demographic data, urgency and duration of surgery, blood loss, urine output, use of intraoperative fluid(s), and blood product(s) were also observed.  Results Of 578 patients enrolled, 116 patients were extubated based on the predefined extubation criteria. Of these, 24 patients were reintubated within 24 hours. ABG parameters such as partial pressure of arterial oxygen (PaO) and serum HCOlevels were significantly lower in the reintubated patients compared to non-reintubated patients (p-values of 0.045 and 0.003, respectively). Conclusion This study showed that the PaO <100 mm Hg or ratio of arterial oxygen partial pressure to fractional inspired oxygen (P/F ratio) of less than 200 and an HCO value of less than 18 are plausible ABG parameters to decide extubation in post-surgery patients in OT. PaCO, base deficit, and lactate were less reliable parameters for planning extubation.

摘要

背景 拔管一直是麻醉的关键环节。已有实现成功拔管的指南和建议,但失败风险始终存在。通过本研究,我们评估术中采集的动脉血气(ABG)值是否有助于预测手术室中的拔管成功率。

材料与方法 这是一项针对血气值不在正常范围内的拔管患者进行的为期一年的前瞻性观察研究。纳入年龄在18岁及以上、接受高风险择期和急诊手术且至少采集了一份术中动脉血样本进行血气分析的患者。除了ABG参数外,还观察了人口统计学数据、手术紧急程度和持续时间、失血量、尿量、术中液体和血液制品的使用情况。

结果 在纳入的578例患者中,116例患者根据预定义的拔管标准进行了拔管。其中,24例患者在24小时内再次插管。与未再次插管的患者相比,再次插管患者的动脉血氧分压(PaO)和血清HCO水平等ABG参数显著更低(p值分别为0.045和0.003)。

结论 本研究表明,PaO<100 mmHg或动脉血氧分压与吸入氧分数之比(P/F比)小于200以及HCO值小于18是决定手术室术后患者拔管的合理ABG参数。PaCO、碱缺失和乳酸是用于规划拔管的可靠性较低的参数。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/215b/9908425/fb1ad5f9251a/cureus-0015-00000033561-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/215b/9908425/b7ac9b3ab153/cureus-0015-00000033561-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/215b/9908425/fb1ad5f9251a/cureus-0015-00000033561-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/215b/9908425/b7ac9b3ab153/cureus-0015-00000033561-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/215b/9908425/fb1ad5f9251a/cureus-0015-00000033561-i02.jpg

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Cumulative Fluid Balance and Outcome of Extubation: A Prospective Observational Study from a General Intensive Care Unit.累积液体平衡与拔管结局:一项来自综合重症监护病房的前瞻性观察研究。
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Analysis of the Risk Factors Associated with Prolonged Intubation or Reintubation after Anterior Cervical Spine Surgery.
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J Korean Med Sci. 2018 Jan 30;33(17):e77. doi: 10.3346/jkms.2018.33.e77. eCollection 2018 Apr 23.
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Risk Factors and Prognosis of Reintubation Following Surgeries under General Anesthesia.全身麻醉下手术后再次插管的危险因素及预后
Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2017 Feb 20;39(1):145-149. doi: 10.3881/j.issn.1000-503X.2017.01.024.
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Risk Factors for Extubation Failure in Extremely Low Birth Weight Infants.极低出生体重儿拔管失败的危险因素
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