对推导的血流动力学参数进行血流动力学压力测量的时机。

Timing of hemodynamic pressure measurements on derived hemodynamic parameters.

作者信息

Urquhart Gayle, Jensen Louise

机构信息

Cardiac Sciences Program, University of Alberta Hospital, Edmonton, Alberta.

出版信息

Dynamics. 2003 Fall;14(3):13-20.

PMID:14725142

Abstract

The purpose of this study was to examine the difference between hemodynamic pressures and parameters obtained pre- compared to post-thermodilution CO measurements. A repeated measures within subject design was conducted with a cardiac surgical cohort. Three measures of hemodynamic pressures and parameters were determined pre- and post-CO measurements (Set 1) and repeated in 30 minutes (Set 2). The sequence was duplicated in four hours (Sets 3 and 4). Hemodynamic pressures lower pre-CO were PAS at Sets 1 and 3, and SBP, DBP, and MAP at Set 3. Hemodynamic parameters lower pre-CO were PVRI at Set 1 and SVRI at Set 3. These pre-post CO differences did not vary by greater than 10%. As the CO injectate volume had minimal effect, hemodynamic pressures may be obtained pre- or post-CO to derive hemodynamic parameters.

摘要

本研究的目的是检验热稀释法测量心输出量（CO）前后所获得的血流动力学压力和参数之间的差异。对心脏外科队列进行了受试者内重复测量设计。在CO测量前后测定了三项血流动力学压力和参数指标（第1组），并在30分钟后重复测量（第2组）。该序列在4小时内重复（第3组和第4组）。CO测量前血流动力学压力较低的情况在第1组和第3组为肺动脉收缩压（PAS），在第3组为收缩压（SBP）、舒张压（DBP）和平均动脉压（MAP）。CO测量前血流动力学参数较低的情况在第1组为肺血管阻力指数（PVRI），在第3组为体血管阻力指数（SVRI）。这些CO测量前后的差异变化不超过10%。由于CO注入量的影响极小，因此可在CO测量前或测量后获取血流动力学压力以推导血流动力学参数。