Ugenti Ippazio, Lattarulo Serafina, Russo Silvana, Ferrarese Filippo, Fabiano Gennaro
Sezione di Chirurgia Generale, Dipartimento di Scienze Chirurgiche Generali Specialistiche, Università degli Studi di Bari.
Chir Ital. 2003 Nov-Dec;55(6):913-8.
Abrikossoff's tumours are better known as granular cell tumours because of the typical microscopic aspect of their cytoplasm. They are uncommon neoplasms, probably of neurogenic origin, typically subepithelial and often benign. Rarely, they may be localised in the digestive tract, where they are mostly asymptomatic and tend to be discovered incidentally during endoscopic examinations indicated for other diseases. Histological examination with immunohistochemical staining usually yields the definitive diagnosis. Most authors agree as to the indication for endoscopic resection because of the possible, though rare, aggressive biological behaviour of these tumours. In the present paper we report on a case of granular cell tumour of the caecum, endoscopically resected and staining positively at the immunohistochemical search for the S100 protein.
阿布里科索夫瘤因其细胞质典型的微观特征而更常被称为颗粒细胞瘤。它们是罕见的肿瘤，可能起源于神经，通常位于上皮下，且多为良性。它们很少会出现在消化道，大多没有症状，往往在因其他疾病进行内镜检查时被偶然发现。通过免疫组织化学染色进行组织学检查通常可得出明确诊断。由于这些肿瘤可能存在（尽管罕见）侵袭性生物学行为，大多数作者都认同内镜切除的指征。在本文中，我们报告了一例盲肠颗粒细胞瘤病例，该病例经内镜切除，免疫组织化学检测S100蛋白呈阳性。
