Melo C R, Melo I S, Schmitt F C, Fagundes R, Amendola D
Department of Pathology, Federal University, Santa Maria, Rio Grande do Sul, Brazil.
Am J Gastroenterol. 1993 Oct;88(10):1785-7.
Granular cell myoblastoma is an uncommon benign tumor that can be located anywhere in the body. Multiple tumors of the gastrointestinal tract are quite rare, having been reported infrequently in the English literature. The histologic, immunohistochemical, and electron microscopic findings in our case, as well as in others reported, suggest that its histogenesis may be related to Schwann cells. One case of multifocal granular cell tumor presenting 52 tumors from the cecum to the sigmoid is described, and the previously reported cases with similar presentation are reviewed. We suggest that in such cases, a long period of observation with repeated colonoscopy may be more appropriate than an aggressive approach.
颗粒细胞瘤是一种罕见的良性肿瘤，可位于身体的任何部位。胃肠道的多发性肿瘤相当罕见，英文文献中鲜有报道。我们病例以及其他报道病例的组织学、免疫组化和电子显微镜检查结果表明，其组织发生可能与施万细胞有关。本文描述了一例从盲肠至乙状结肠出现52个肿瘤的多灶性颗粒细胞瘤病例，并对先前报道的类似病例进行了回顾。我们建议，对于此类病例，长期观察并反复进行结肠镜检查可能比积极的治疗方法更为合适。
