毛里求斯肾移植和骨髓移植供受者中HLA - B27的患病率。

Prevalence of HLA-B27 among donors and recipients for renal and bone marrow transplantation in Mauritius.

作者信息

Sun M Chan, Kissoon M, Sonoo J, Subratty A H

机构信息

Department of Health and Medical Sciences, Faculty of Science, University of Mauritius, Reduit, Mauritius.

出版信息

Br J Biomed Sci. 2003;60(4):221-2.

PMID:14725339

Abstract

In this study, the frequency of the tissue antigen HLA-B27 is studied in 494 donors and recipients for renal and bone marrow transplantation on the multi-ethnic island of Mauritius, the majority of the population of which is of Indian descent. Although results showed a prevalence rate of 4.3%, inter-racial variation was not observed between the major ethnic groups (P>0.05). These findings are comparable with the results of studies on HLA-B27 prevalence rate in India, and lend support to the argument that the HLA-B27 test should not be used on a routine basis to diagnose HLA-B27-related rheumatic disorders in Mauritius.

摘要

在这项研究中，对毛里求斯这个多民族岛屿上494名肾脏和骨髓移植供体及受体的组织抗原HLA - B27频率进行了研究，该岛人口大多数为印度裔。尽管结果显示患病率为4.3%，但主要种族群体之间未观察到种族差异（P>0.05）。这些发现与印度关于HLA - B27患病率的研究结果相当，并支持了在毛里求斯不应将HLA - B27检测作为常规手段来诊断HLA - B27相关风湿性疾病这一观点。