Addington J, Williams J, Young J, Addington D
Department of Psychiatry, University of Calgary, Calgary, Alberta, Canada.
Acta Psychiatr Scand. 2004 Feb;109(2):116-20. doi: 10.1046/j.0001-690x.2003.00232.x.
This was to determine the prevalence of suicidal behaviours prior to and during the first year of treatment in a comprehensive early psychosis program (EPP) and to identify predictors of suicidal behaviour.
In a cohort study of 238 subjects, patients were assessed at initial presentation to an EPP and 1 year later. Measures included a range of demographic variables, suicide attempts, depression, positive and negative symptoms, social functioning and substance misuse.
Although 15.1% attempted suicide prior to program entry, only 2.9% made an attempt in the year after program entry and 0.4% completed suicide. No further attempts were seen in those with previous parasuicide. These rates are lower than other published rates for first-episode patients.
It is possible that specifically designed first-episode programs can reduce the suicidal behaviour in this high-risk population. The low prevalence of attempted suicide makes modeling predictors difficult.
本研究旨在确定在一个综合性早期精神病项目（EPP）治疗的第一年之前及期间自杀行为的发生率，并识别自杀行为的预测因素。
在一项对238名受试者的队列研究中，患者在首次进入EPP时及1年后接受评估。测量指标包括一系列人口统计学变量、自杀未遂情况、抑郁、阳性和阴性症状、社会功能以及物质滥用情况。
尽管15.1%的患者在进入项目前曾试图自杀，但在进入项目后的一年中只有2.9%的患者有过自杀企图，0.4%的患者自杀身亡。既往有准自杀行为的患者未再出现自杀企图。这些发生率低于其他已发表的首发患者的发生率。
专门设计的首发项目有可能降低这一高危人群的自杀行为。自杀未遂的低发生率使得对预测因素进行建模变得困难。
