Austad Gudrun, Joa Inge, Johannessen Jan Olav, Larsen Tor Ketil
Psychiatric Division, Regional Centre for Clinical Research in Psychosis, Stavanger University Hospital, Stavanger, Norway.
Faculty of Social Sciences, University of Stavanger, Stavanger, Norway.
Early Interv Psychiatry. 2015 Aug;9(4):300-7. doi: 10.1111/eip.12113. Epub 2013 Dec 5.
Prior research shows contradictory gender patterns in suicidal behaviour among patients with first-episode psychosis. The aim of this study was to investigate gender differences in the prevalence of suicidal behaviour (suicidal ideation, suicide plans and suicide attempts) and to delineate risk factors for suicidal behaviour among consecutively included male and female patients with first-episode psychosis in the TIPS II early detection study.
Patients with first-episode psychosis (n = 246) from a hospital catchment area with a system for early detection were assessed and compared on baseline sociodemographical and clinical variables according to gender. Current (past 1 month) and lifetime prevalence of suicidal behaviour were assessed.
Current and lifetime rates of suicidal behaviour were high (50.8% and 65.9%, respectively) and higher among females (lifetime: 78.3 %, past month: 64.2 %) versus males (lifetime: 56.4 %, past month: 40.7 %). Depressive symptoms and female gender were associated with both lifetime and current risk for suicidal behaviour. Lifetime prevalence was also associated with a longer duration of untreated psychosis and young age after controlling for other risk factors.
Suicidal behaviour was frequent among patients with first-episode psychosis, with a higher prevalence of suicidal behaviour in females. Depressive symptoms and female gender were significantly associated with suicidal behaviour.
先前的研究显示，首发精神病患者的自杀行为存在相互矛盾的性别模式。本研究的目的是调查自杀行为（自杀意念、自杀计划和自杀未遂）患病率的性别差异，并在TIPS II早期检测研究中，对连续纳入的首发精神病男性和女性患者的自杀行为危险因素进行描述。
对来自设有早期检测系统的医院服务区域的首发精神病患者（n = 246），根据性别对基线社会人口统计学和临床变量进行评估和比较。评估自杀行为的当前（过去1个月）和终生患病率。
自杀行为的当前和终生发生率都很高（分别为50.8%和65.9%），女性（终生：78.3%，过去1个月：64.2%）高于男性（终生：56.4%，过去1个月：40.7%）。抑郁症状和女性性别与自杀行为的终生和当前风险均相关。在控制其他危险因素后，终生患病率还与未治疗精神病的持续时间较长和年龄较小有关。
首发精神病患者中自杀行为很常见，女性自杀行为的患病率更高。抑郁症状和女性性别与自杀行为显著相关。
