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[A new method of global search for functional DNA segments using a fractal representation of nucleotide texts].

作者信息

Korolev S E, Solov'ev V V, Tumanian V G

出版信息

Biofizika. 1992 Sep-Oct;37(5):837-47.

PMID:1472562
Abstract

New global method for computer prediction of functional sites in nucleotide sequences, based on the fractal representation, is presented. Fractal representation of set of sequences (FRS) provides simple way for generating recognitions matrix of functionally similar sequences and simple estimations of its efficiency for searching homologous regions in new sequences. Other advantages of the method are absence of the necessity of sequences alignment during generating based set and searching new homologous regions and small CPU time. Usage of the method illustrated for searching globin and histone genes, for ALU repeats in human genome and long terminal repeats in virus genome.

摘要

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