Weaver Seymour M, Sagaral Emelou C
Advanced Laser and Cosmetic Dermatology, 4007 GG Bellaire Boulevard, Houston, TX 77025, USA.
Dermatol Surg. 2003 Dec;29(12):1187-91. doi: 10.1111/j.1524-4725.2003.29387.x.
Pseudofolliculitis barbae (PFB) is a foreign body inflammatory condition that is caused by in-grown hairs of the face and body. An effective treatment to alleviate this condition without the risk of side effects has yet to be found.
The objective of this study was to evaluate the Lyra 1064-nm long-pulse ND:YAG laser in the treatment of PFB on skin types V and VI.
Twenty subjects (12 males and 8 females) were given two treatments approximately 3 to 4 weeks apart and were assessed by objective papule/pustule and hair counts at 1, 2, and 3 months after final treatment. Laser treatments with the Lyra Nd:YAG laser were applied onto 2x2-cm regions on the upper and lower mandible and neck regions. Contralateral controls were used to assess overall effectiveness. Subjective evaluations were also obtained from both subjects and investigators. Assessments of any abnormal side effects caused by laser treatment, including dyspigmentation and/or scarring, were also evaluated.
A reduction in the quantity of papules/pustules and hairs when compared with baseline data was statistically significant for treatment of PFB in the mandibular and neck regions at the 1-, 2-, and 3-month follow-up evaluations. Subject evaluations ranged from satisfied to very satisfied. Side effects included transient hyperpigmentation, transient hypopigmentation, mild erythema, and itching.
The use of the 1064-nm long-pulse Nd:YAG laser for the treatment and management of PFB on skin types V and VI is both safe and effective, with positive results lasting for up for to 3 months after two treatments.
须部假性毛囊炎（PFB）是一种异物性炎症性疾病，由面部和身体毛发向内生长引起。尚未找到一种能有效缓解该病症且无副作用风险的治疗方法。
本研究的目的是评估Lyra 1064纳米长脉冲钕：钇铝石榴石激光治疗V型和VI型皮肤的须部假性毛囊炎的效果。
20名受试者（12名男性和8名女性）接受了两次间隔约3至4周的治疗，并在最后一次治疗后的1、2和3个月通过客观丘疹/脓疱和毛发计数进行评估。使用Lyra钕：钇铝石榴石激光对上下颌骨和颈部区域的2×2厘米区域进行治疗。使用对侧对照来评估总体疗效。还从受试者和研究者处获得主观评价。同时评估激光治疗引起的任何异常副作用，包括色素沉着和/或瘢痕形成。
在1、2和3个月的随访评估中，与基线数据相比，下颌和颈部区域治疗PFB时丘疹/脓疱和毛发数量减少具有统计学意义。受试者评价从满意到非常满意。副作用包括短暂性色素沉着、短暂性色素减退、轻度红斑和瘙痒。
使用1064纳米长脉冲钕：钇铝石榴石激光治疗V型和VI型皮肤的须部假性毛囊炎是安全有效的，两次治疗后阳性结果可持续长达3个月。
