Chaín Myriam, Dei-Cas Ignacio, Carbia Sergio, Xifra Mariana, Wright Dolores, Glorio Roberto, Devés Alberto, Woscoff Alberto
Dermatology Division, Hospital de Clinicas, University of Buenos Aires School of Medicine, Córdoba 2351, Buenos Aires 1120, Argentina.
J Am Acad Dermatol. 2004 Feb;50(2 Suppl):S9-10. doi: 10.1016/s0190-9622(03)00446-8.
True histiocytic malignancies (THM) are controversial disorders that are being re-evaluated with modern cellular and molecular biology techniques. True histiocytic lymphoma (THL) is a low-incidence, poor-prognosis THM. It mainly affects the skin, gastrointestinal tract, and bone tissues. Occasionally, skin lesions are the presenting clinical features. A patient with initially cutaneous THL is described. This and other reported cases confirm that THM are a nosologic entity by themselves.
真性组织细胞性恶性肿瘤（THM）是一类存在争议的疾病，目前正通过现代细胞和分子生物学技术进行重新评估。真性组织细胞性淋巴瘤（THL）是一种发病率低、预后差的THM。它主要累及皮肤、胃肠道和骨组织。偶尔，皮肤损害是其首发临床特征。本文描述了一例最初表现为皮肤型THL的患者。该病例及其他已报道的病例证实，THM本身是一种独立的疾病实体。
