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台湾某大学医院的营养变异型链球菌感染:疾病出现及β-内酰胺和大环内酯耐药的高流行率

Nutritionally variant streptococcal infections at a University Hospital in Taiwan: disease emergence and high prevalence of beta-lactam and macrolide resistance.

作者信息

Liao Chung-Hsin, Teng Lee-Jene, Hsueh Po-Ren, Chen Yu-Chi, Huang Li-Min, Chang Shan-Chwen, Ho Shen-Wu

机构信息

Department of Laboratory Medicine, National Taiwan University Hospital, Taipei, Taiwan.

出版信息

Clin Infect Dis. 2004 Feb 1;38(3):452-5. doi: 10.1086/381098. Epub 2004 Jan 9.

DOI:10.1086/381098
PMID:14727223
Abstract

From January 1993 to December 2002, 28 patients with nutritionally variant streptococci (NVS) infections were treated at a university hospital in Taiwan. Twelve (43%) of these patients had various underlying malignancies, and 7 (25%) had underlying valvular heart diseases. Nine patients (32%) had infective endocarditis, and 9 (32%) had primary bacteremia. The deaths of 7 patients (25%) were directly related to NVS infection. Among the 28 isolates recovered from these patients, 50% were not susceptible to penicillin, 33% were not susceptible to cefotaxime, and 93% were not susceptible to azithromycin.

摘要

1993年1月至2002年12月,台湾一所大学医院收治了28例营养变异型链球菌(NVS)感染患者。其中12例(43%)患者患有各种潜在恶性肿瘤,7例(25%)患有潜在瓣膜性心脏病。9例(32%)患者发生感染性心内膜炎,9例(32%)发生原发性菌血症。7例(25%)患者死亡与NVS感染直接相关。从这些患者中分离出的28株菌株中,50%对青霉素不敏感,33%对头孢噻肟不敏感,93%对阿奇霉素不敏感。

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