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[消炎药物系列治疗慢性非细菌性前列腺炎的临床试验]

[Clinical trials of antiphlogistic agent series in treating chronic nonbacterial prostatitis].

作者信息

Peng Shao-Fang, Yang Zhi-Zhong, Lin Xiao-Fen, Li Shao-Fen, Xie Zi, Cai Jing, Yu Li-Chao

机构信息

Research Institute of Infertility, Shantou Hospital of Traditional Chinese Medicine, Shantou, Guangdong 515031, China.

出版信息

Zhonghua Nan Ke Xue. 2003 Dec;9(9):716-9.

PMID:14727367
Abstract

OBJECTIVE

To investigate the curative effect of antiphlogistic agent series on treating chronic nonbacterial prostatitis (CNP).

METHODS

One hundred and sixty patients were randomized into 4 groups for an 8-week clinical observation: group A (oral antiphlogistic medicinal granules only), group B (oral antiphlogistic medicinal granules + retention enema), group C (oral antiphlogistic medicinal granules + rectal), and group D (antiphlogistic medicinal granules + rectally + hip bath). Single blind trials were employed.

RESULTS

The curative rates of the 4 groups were 37.5%, 57.5%, 52.5% and 82.5% respectively, while the total efficacy rates were 42.5%, 82.5%, 77.5% and 92.5% respectively. Compared with groups A, B and C, the curative rate of group D was significantly higher (P < 0.05). The difference in efficacy rates was slight between groups B and D (P < 0.05), but significant between groups A and C (P < 0.05).

CONCLUSIONS

Combined treatment therapy can improve the effect of CNP treatment and clear away heat and toxic material. The antiphlogistic agent series, with the effect of motivating blood circulation and removing blood stasis, turned out to be an effective traditional Chinese medicine in treating CNP.

摘要

目的

探讨消炎系列制剂治疗慢性非细菌性前列腺炎(CNP)的疗效。

方法

将160例患者随机分为4组,进行为期8周的临床观察:A组(仅口服消炎冲剂)、B组(口服消炎冲剂+保留灌肠)、C组(口服消炎冲剂+直肠给药)、D组(消炎冲剂+直肠给药+坐浴)。采用单盲试验。

结果

4组的治愈率分别为37.5%、57.5%、52.5%和82.5%,总有效率分别为42.5%、82.5%、77.5%和92.5%。与A、B、C组相比,D组治愈率显著更高(P<0.05)。B组和D组有效率差异较小(P<0.05),但A组和C组之间差异显著(P<0.05)。

结论

综合治疗可提高CNP的治疗效果并清热排毒。消炎系列制剂具有活血化瘀作用,是治疗CNP的有效中药。

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