Report of the Twelfth International Meeting of the OIE Ad hoc Group on Non Tsetse-Transmitted Animal Trypanosomosis. Paris, 15 May 1991.

Studies of Trypanosoma evansi strains of widely varied origin (Africa, Asia, South America) have continued, leading to two groups of diagnostic procedures, tested first in the laboratory and then in the field: the card agglutination trypanosomosis test and the enzyme-linked immunosorbent assay to supplement microscopic examination of smears. A microscopy procedure for differentiating Trypanosoma species in smears was proposed. Diagnostic kits have again been made available free of charge to interested and suitably qualified research workers. Several research workers have studied the lymphokines induced by T. evansi, and the question of the potential therapeutic use of these substances was raised. Research workers in Asia were increasingly involved in various problems associated with T. evansi, including fundamental research and potential applications in the field. The epidemiology of T. evansi infections has been the subject of numerous research projects in Asia and South America. Research on trypanocides has confirmed the activity of Cymelarsan, which has since been marketed, the properties of the new derivative T46 (pharmacokinetic studies) and the value of in vitro and in vivo comparisons of currently available trypanocides. The sphere of interest of the Group was extended to cover all forms of animal trypanosomosis not transmitted by tsetse flies.