Wei Yongxiang, Han Demin, Cai Zhen, Yang Ling, Liu Xiaochao, Xian Mu, Zhang Xiaobin
Department of Otolaryngology-Head and Neck Surgery, Affiliated Beijing Tongren Hospital, Capital University of Medical Sciences, Beijing 100730.
Lin Chuang Er Bi Yan Hou Ke Za Zhi. 2003 Oct;17(10):618-20.
To observe olfactory evoked potential(OEPs) produced by electrical stimulation of the olfactory mucosa and to find out an objective way to appraise olfactory function.
A bipolar stimulus electrode was placed on the olfactory mucosa of adult health rabbits via anterior naris. Olfactory evoked potential was recorded at headtop after being given a 0.5-4.0 mA current to the mucosa. And we also investigated the effect of stimulus parameters and stimulus location to the wave form of OEPs.
Triphasic negative-positive-negative evoked potentials were recorded from the surface of the frontal head close to olfactory bulb. Latent period of three waves respectively was N(1)20.6 ms, P(1)33.5 ms, N(2)58.3 ms.
In general, the OEPs were composed of triphasic negative-positive-negative complexes. The waveforms were stable and could be repeated well. Each parameter was useful for estimating the olfactory function.
观察电刺激嗅黏膜产生的嗅觉诱发电位(OEPs),并找出一种评估嗅觉功能的客观方法。
将双极刺激电极经前鼻孔置于成年健康兔的嗅黏膜上。向黏膜施加0.5 - 4.0 mA电流后,在头顶记录嗅觉诱发电位。并且我们还研究了刺激参数和刺激位置对嗅觉诱发电位波形的影响。
在靠近嗅球的额头部表面记录到三相负-正-负诱发电位。三个波的潜伏期分别为N(1)20.6 ms、P(1)33.5 ms、N(2)58.3 ms。
一般来说,嗅觉诱发电位由三相负-正-负复合波组成。波形稳定且可重复性良好。每个参数对评估嗅觉功能都有用。