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[家兔嗅觉诱发电位的实验研究]

[Experimental study on olfactory evoked potential in rabbits].

作者信息

Wei Yongxiang, Han Demin, Cai Zhen, Yang Ling, Liu Xiaochao, Xian Mu, Zhang Xiaobin

机构信息

Department of Otolaryngology-Head and Neck Surgery, Affiliated Beijing Tongren Hospital, Capital University of Medical Sciences, Beijing 100730.

出版信息

Lin Chuang Er Bi Yan Hou Ke Za Zhi. 2003 Oct;17(10):618-20.

PMID:14727437
Abstract

OBJECTIVE

To observe olfactory evoked potential(OEPs) produced by electrical stimulation of the olfactory mucosa and to find out an objective way to appraise olfactory function.

METHOD

A bipolar stimulus electrode was placed on the olfactory mucosa of adult health rabbits via anterior naris. Olfactory evoked potential was recorded at headtop after being given a 0.5-4.0 mA current to the mucosa. And we also investigated the effect of stimulus parameters and stimulus location to the wave form of OEPs.

RESULT

Triphasic negative-positive-negative evoked potentials were recorded from the surface of the frontal head close to olfactory bulb. Latent period of three waves respectively was N(1)20.6 ms, P(1)33.5 ms, N(2)58.3 ms.

CONCLUSION

In general, the OEPs were composed of triphasic negative-positive-negative complexes. The waveforms were stable and could be repeated well. Each parameter was useful for estimating the olfactory function.

摘要

目的

观察电刺激嗅黏膜产生的嗅觉诱发电位(OEPs),并找出一种评估嗅觉功能的客观方法。

方法

将双极刺激电极经前鼻孔置于成年健康兔的嗅黏膜上。向黏膜施加0.5 - 4.0 mA电流后,在头顶记录嗅觉诱发电位。并且我们还研究了刺激参数和刺激位置对嗅觉诱发电位波形的影响。

结果

在靠近嗅球的额头部表面记录到三相负-正-负诱发电位。三个波的潜伏期分别为N(1)20.6 ms、P(1)33.5 ms、N(2)58.3 ms。

结论

一般来说,嗅觉诱发电位由三相负-正-负复合波组成。波形稳定且可重复性良好。每个参数对评估嗅觉功能都有用。

相似文献

1
[Experimental study on olfactory evoked potential in rabbits].[家兔嗅觉诱发电位的实验研究]
Lin Chuang Er Bi Yan Hou Ke Za Zhi. 2003 Oct;17(10):618-20.
2
[Olfactory evoked potentials produced by electrical stimulation of the olfactory mucosa].[电刺激嗅黏膜产生的嗅觉诱发电位]
Zhonghua Er Bi Yan Hou Ke Za Zhi. 1999 Aug;34(4):224-6.
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Olfactory evoked potentials produced by electrical stimulation of the olfactory mucosa.由电刺激嗅黏膜产生的嗅觉诱发电位。
Auris Nasus Larynx. 1996;23:98-104. doi: 10.1016/s0385-8146(96)80015-0.
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Olfactory evoked potentials: experimental and clinical studies.嗅觉诱发电位:实验与临床研究
J Neurosurg. 1996 Dec;85(6):1122-6. doi: 10.3171/jns.1996.85.6.1122.
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[Electrically stimulated olfactory evoked potential in olfactory-lesioned rabbit].[嗅觉损伤兔的电刺激嗅觉诱发电位]
Zhonghua Er Bi Yan Hou Ke Za Zhi. 2004 Jan;39(1):36-9.
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Olfactory evoked potential produced by electrical stimulation of the human olfactory mucosa.电刺激人类嗅黏膜产生的嗅觉诱发电位。
Chem Senses. 1997 Feb;22(1):77-81. doi: 10.1093/chemse/22.1.77.
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Trigeminal evoked potentials in man: a new olfactory stimulation device.人类三叉神经诱发电位:一种新型嗅觉刺激装置。
Funct Neurol. 1998 Apr-Jun;13(2):135-40.
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In vivo electrical stimulation of rabbit retina with a microfabricated array: strategies to maximize responses for prospective assessment of stimulus efficacy and biocompatibility.使用微纳加工阵列对兔视网膜进行体内电刺激:用于前瞻性评估刺激效果和生物相容性的最大化反应策略。
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