Greenberg Paul E, Kessler Ronald C, Birnbaum Howard G, Leong Stephanie A, Lowe Sarah W, Berglund Patricia A, Corey-Lisle Patricia K
Analysis Group, Inc., Boston, MA 02199, USA.
J Clin Psychiatry. 2003 Dec;64(12):1465-75. doi: 10.4088/jcp.v64n1211.
The economic burden of depression was estimated to be 43.7 billion dollars in 1990. A subsequent study reported a cost burden of 52.9 billion dollars using revised prevalence data and a refined workplace cost estimation approach. The objective of the current report is to provide a 10-year update of these estimates using the same methodological framework.
Using a human capital approach, we developed prevalence-based estimates of 3 major cost categories: (1) direct costs, (2) mortality costs arising from depression-related suicides, and (3) costs associated with depression in the workplace. Cost-of-illness estimates from 1990 were updated to reflect the experience in 2000 using current epidemiologic data and publicly available population, wage, and cost information.
Whereas the treatment rate of depression increased by over 50%, its economic burden rose by only 7%, going from 77.4 billion dollars in 1990 (inflation-adjusted dollars) to 83.1 billion dollars in 2000. Of the 2000 total, 26.1 billion dollars (31%) were direct medical costs, 5.4 billion dollars (7%) were suicide-related mortality costs, and 51.5 billion dollars (62%) were workplace costs.
The economic burden of depression remained relatively stable between 1990 and 2000, despite a dramatic increase in the proportion of depression sufferers who received treatment. Future research will incorporate additional costs associated with depression sufferers, including the excess costs of their coexisting psychiatric and medical conditions and attention to the role of painful conditions as a driver of these costs.
1990年抑郁症的经济负担估计为437亿美元。随后一项研究使用修订后的患病率数据和改进的工作场所成本估算方法报告了529亿美元的成本负担。本报告的目的是使用相同的方法框架对这些估计进行10年更新。
我们采用人力资本方法,对三大成本类别进行了基于患病率的估计:(1)直接成本,(2)抑郁症相关自杀导致的死亡成本,以及(3)工作场所与抑郁症相关的成本。根据当前的流行病学数据以及公开可得的人口、工资和成本信息,对1990年的疾病成本估计进行了更新,以反映2000年的情况。
尽管抑郁症的治疗率提高了50%以上,但其经济负担仅上升了7%,从1990年的774亿美元(经通胀调整后的美元)增至2000年的831亿美元。在2000年的总成本中,261亿美元(31%)为直接医疗成本,54亿美元(7%)为与自杀相关的死亡成本,515亿美元(62%)为工作场所成本。
1990年至2000年期间,抑郁症的经济负担保持相对稳定,尽管接受治疗的抑郁症患者比例大幅增加。未来的研究将纳入与抑郁症患者相关的其他成本,包括其并存的精神和医疗状况的额外成本,并关注疼痛状况作为这些成本驱动因素的作用。