用于基因组和蛋白质组数据生物学解释的基因本体工具的开发。
Development of gene ontology tool for biological interpretation of genomic and proteomic data.
作者信息
Feng Weimin, Wang Geoffrey, Zeeberg Barry R, Guo Kejiao, Fojo Anthony T, Kane David W, Reinhold William C, Lababidi Samir, Weinstein John N, Wang May D
机构信息
The Wallace H Coulter Biomedical Engineering Department, Georgia Institute of Technology and Emory University, Atlanta GA 30332-0535, USA.
出版信息
AMIA Annu Symp Proc. 2003;2003:839.
We have designed and developed a Gene Ontology based navigation tool, GoMiner, which organizes lists of interesting genes from a microarray or a protein array experiment for biological interpretation. It provides quantitative and statistical output files and useful visualization (e.g., a tree-like structure) to map the list of genes to its biological functional categories. It also provides links to other resources such as pubmed, locuslink, and biological molecular interaction map and signaling pathway packages.
我们设计并开发了一种基于基因本体论的导航工具GoMiner，它对来自微阵列或蛋白质阵列实验的感兴趣基因列表进行整理，以进行生物学解释。它提供定量和统计输出文件以及有用的可视化工具（例如，树状结构），将基因列表映射到其生物学功能类别。它还提供到其他资源的链接，如PubMed、LocusLink以及生物分子相互作用图谱和信号通路软件包。
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