Hosack Douglas A, Dennis Glynn, Sherman Brad T, Lane H Clifford, Lempicki Richard A
Laboratory of Immunopathogenesis and Bioinformatics, PO Box B, SAIC-Frederick, Inc, Frederick, MD 21702, USA.
Genome Biol. 2003;4(10):R70. doi: 10.1186/gb-2003-4-10-r70. Epub 2003 Sep 11.
EASE is a customizable software application for rapid biological interpretation of gene lists that result from the analysis of microarray, proteomics, SAGE and other high-throughput genomic data. The biological themes returned by EASE recapitulate manually determined themes in previously published gene lists and are robust to varying methods of normalization, intensity calculation and statistical selection of genes. EASE is a powerful tool for rapidly converting the results of functional genomics studies from 'genes' to 'themes'.
EASE是一款可定制的软件应用程序，用于对因微阵列、蛋白质组学、SAGE及其他高通量基因组数据分析而产生的基因列表进行快速生物学解读。EASE返回的生物学主题概括了先前发表的基因列表中手动确定的主题，并且对于不同的标准化方法、强度计算和基因统计选择具有稳健性。EASE是一个将功能基因组学研究结果从“基因”快速转化为“主题”的强大工具。
