Xu Feng-sen, Liu Jian-xin, Zhang Shu-ping, Li Juan, Su Qin
Department of Obstetrics and Gynecology, Qingdao Municipal Hospital, Qingdao 266011, China.
Zhonghua Fu Chan Ke Za Zhi. 2003 Dec;38(12):724-6.
To study the related factors of postpartum depression (PPD) and the effects of intervening measures to PPD incidence.
1 597 pregnant women selected from our antenatal care clinic were investigated by using the hospital anxiety and depression questionnaire (HAD) during pregnancy and the Edinburgh postpartum depression scale (EPDS) after childbirth. All the enrolled women were randomly divided into control group and intervening group by the proportion of 1 to 2. Six intervening measures were used in the latter group.
(1) There were 49 women whose HAD >or= 11 score (anxiety-depression mood) with 28 cases (57.1%) had got postpartum depression in the control group. In the intervening group, however, there were 94 women whose HAD >or= 11 score with 24 cases (25.5%) had got postpartum depression. There is a significant difference between the two groups (P < 0.01). (2) There were 71 (13.0%) women whose EPDS >or= 13 score (postpartum depression) in the control group. In the intervening group, however, there were 63 (6.0%) women whose EPDS >or= 13 score. There had a significant difference between the two groups (P < 0.01). (3) PPD women had higher N and P scores than those of non-PPD women (P < 0.01).
(1) Prenatal anxiety, depression, negative personality and postpartum psychological and physiological changes were high risk factors to PPD. (2) Psychological personality play an important role in PPD. (3) Incidence of PPD was significantly reduced by social support.
探讨产后抑郁症（PPD）的相关因素及干预措施对PPD发生率的影响。
选取我院产前检查门诊的1597例孕妇，于孕期采用医院焦虑抑郁量表（HAD）进行调查，产后采用爱丁堡产后抑郁量表（EPDS）进行调查。所有入选孕妇按1∶2的比例随机分为对照组和干预组，对干预组采用6种干预措施。
（1）对照组中HAD≥11分（焦虑抑郁情绪）的孕妇有49例，其中产后抑郁28例（57.1%）；干预组中HAD≥11分的孕妇有94例，其中产后抑郁24例（25.5%）。两组比较差异有统计学意义（P<0.01）。（2）对照组中EPDS≥13分（产后抑郁）的孕妇有71例（13.0%）；干预组中EPDS≥13分的孕妇有63例（6.0%）。两组比较差异有统计学意义（P<0.01）。（3）PPD组孕妇的N、P分高于非PPD组孕妇（P<0.01）。
（1）产前焦虑、抑郁、负性人格及产后心理生理变化是PPD的高危因素。（2）心理人格在PPD中起重要作用。（3）社会支持可显著降低PPD的发生率。
