门静脉高压症：回归胎儿状态以再次尝试分化？

Portal hypertension: return to fetal life to re-attempt differentiation?

作者信息

Aller M A, López L, Nava M P, Arias J L, Durán H J, Arias J

机构信息

Surgery Department I, School of Medicine, Complutense University of Madrid, Spain.

出版信息

Med Hypotheses. 2004;62(1):79-81. doi: 10.1016/s0306-9877(03)00275-5.

DOI:10.1016/s0306-9877(03)00275-5

PMID:14729008

Abstract

We speculate on the final meaning of the alterations that characterize portal hypertensive enteropathy. The similarity of these alterations with certain morphofunctional characteristics of prenatal splanchnic development makes it possible to hypothesize that the dedifferentiation with return to early stages of development could constitute a portal hypertension induced pathogenic mechanism.

摘要

我们推测了门静脉高压性肠病特征性改变的最终意义。这些改变与产前内脏发育的某些形态功能特征相似，这使得我们有可能假设，向发育早期阶段回归的去分化可能构成一种门静脉高压诱导的致病机制。